MUC4 enhances gemcitabine resistance and malignant behaviour in pancreatic cancer cells expressing cancer-associated short O-glycans.
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DOI: 10.1016/j.canlet.2021.01.015
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is highly lethal. MUC4 (mucin4) is a heavily glycosylated protein aberrantly expressed in PDAC and promotes tumorigenesis via an unknown mechanism. To assess this, we genetically knocked out (KO) MUC4 in… read more here.
Keywords: pdac cells; pdac; gemcitabine resistance; muc4 enhances ... See more keywords