The role of the XBP-1/AGR2 signaling pathway in the regulation of airway Mucin5ac hypersecretion under hypoxia.
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DOI: 10.1016/j.yexcr.2019.05.023
Abstract: Oversecretion of Mucin5ac (MUC5AC), which is primarily synthesized by goblet cells and is the major gel-forming mucin, is a hallmark of various pulmonary inflammatory diseases. Hypoxia is considered a common pathophysiologic feature in various pulmonary… read more here.
Keywords: hif; agr2; muc5ac hypersecretion; hypersecretion ... See more keywords