Type IV collagen reduces mucin 5AC secretion in three-dimensional cultured human primary airway epithelial cells
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2019.100707
Abstract: Mucin 5AC (MUC5AC) hypersecretion induces airway narrowing in patients with asthma, which leads to breathing problems. We investigated the regulation of MUC5AC secretion by extracellular matrix (ECM) proteins in human primary airway epithelial cells from… read more here.
Keywords: muc5ac secretion; secretion; primary airway; human primary ... See more keywords
Type IV collagen reduces MUC5AC secretion in the lungs of ovalbumin-sensitized mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.851374
Abstract: Mucin 5AC (MUC5AC) is excessively secreted in the respiratory tract of patients with asthma. Suppressing this secretion is important for improving the air passages, which facilitates easy breathing. We have previously reported that the addition… read more here.
Keywords: type collagen; muc5ac secretion; collagen; sensitized mice ... See more keywords