Mucin‐Like Glycoproteins Modulate Interfacial Properties of a Mimetic Ocular Epithelial Surface
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Science"
DOI: 10.1002/advs.202100841
Abstract: Abstract Dry eye disease (DED) has high personal and societal costs, but its pathology remains elusive due to intertwined biophysical and biochemical processes at the ocular surface. Specifically, mucin deficiency is reported in a subset… read more here.
Keywords: interfacial properties; mucin; surface; mucin like ... See more keywords
HEG1 is a novel mucin-like membrane protein that serves as a diagnostic and therapeutic target for malignant mesothelioma
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep45768
Abstract: The absence of highly specific markers for malignant mesothelioma (MM) has served an obstacle for its diagnosis and development of molecular-targeting therapy against MM. Here, we show that a novel mucin-like membrane protein, sialylated protein… read more here.
Keywords: mesothelioma; target; novel mucin; mucin like ... See more keywords
Contrasting the Conformational Effects of α-O-GalNAc and α-O-Man Glycan Protein Modifications and their Impact on the Mucin-Like Region of alpha-Dystroglycan.
Sign Up to like & getrecommendations! Published in 2020 at "Glycobiology"
DOI: 10.1093/glycob/cwaa112
Abstract: We have carried out a comparative study of the conformational impact of modifications to threonine residues of either α-O-Man or α-O-GalNAc in the context of a sequence from the mucin-like region of α-dystroglycan. Both such… read more here.
Keywords: contrasting conformational; conformational effects; man; mucin like ... See more keywords
Apical Secretory Glycoprotein Complex Contributes to Cell Attachment and Entry by Cryptosporidium parvum
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DOI: 10.1128/mbio.03064-22
Abstract: Although Cryptosporidium is extremely efficient at penetrating mucus and invading epithelial cells in the intestine, the mechanism of cell attachment is poorly understood. To expand our understanding of this process, we characterized the antigens recognized… read more here.
Keywords: cell; cell attachment; cryptosporidium parvum; mucin like ... See more keywords
Mucins and Pathogenic Mucin-Like Molecules Are Immunomodulators During Infection and Targets for Diagnostics and Vaccines
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2019.00710
Abstract: Mucins and mucin-like molecules are highly O-glycosylated proteins present on the cell surface of mammals and other organisms. These glycoproteins are highly diverse in the apoprotein and glycan cores and play a central role in… read more here.
Keywords: molecules immunomodulators; mucins mucin; like molecules; mucins pathogenic ... See more keywords
A Mucin-Like Protein Is Essential for Oviposition in Nilaparvata lugens
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.00551
Abstract: Mucins play a variety of roles; for example, in vertebrates, mucins lubricate epithelial surfaces and protect tissue from physical and biological damage, however, knowledge of insect mucins is limited. Here, we identified an eggshell-related mucin-like… read more here.
Keywords: oviposition; essential oviposition; like protein; nilaparvata lugens ... See more keywords
Sogatella furcifera Saliva Mucin-like Protein Is Required for Feeding and Induces Rice Defences
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158239
Abstract: The white-backed planthopper (WBPH), Sogatella furcifera, is one of the most important piercing-sucking pests of rice (Oryza sativa) in Asia. Mucin-like salivary protein (SFMLP) is highly expressed in the salivary glands of WBPH, which plays… read more here.
Keywords: rice plants; wbph; rice; mucin like ... See more keywords