Articles with "muciniphila" as a keyword



Probiotic Engraftment of Akkermansia muciniphila in an In Vitro Synthetic Microbial Community

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Published in 2025 at "Microbial Ecology"

DOI: 10.1007/s00248-025-02605-1

Abstract: Akkermansia muciniphila is a specialist mucin glycan-degrader that is common in the human gut. A. muciniphila is associated with host health and therefore proposed as a next-generation probiotic. However, it is unknown if consumption of… read more here.

Keywords: muciniphila; mucin glycan; akkermansia muciniphila; engraftment ... See more keywords

Akkermansia muciniphila fermentation culture based on a novel bionic large intestine dynamic digestion model

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Published in 2021 at "Food bioscience"

DOI: 10.1016/j.fbio.2021.101260

Abstract: Abstract Akkermansia muciniphila, a member of the human intestinal microflora, is a potential next-generation probiotic. Therefore, the optimization of in vitro culture conditions for A. muciniphila is a promising research direction. In this study, an… read more here.

Keywords: large intestine; muciniphila; intestine dynamic; bionic large ... See more keywords

The effects of feed supplementing Akkemansia muciniphila on incidence, severity, and gut microbiota of necrotic enteritis in chickens

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Published in 2022 at "Poultry Science"

DOI: 10.1016/j.psj.2022.101751

Abstract: Akkermansia muciniphila (AM) is a mucin-degrading anaerobe, exerting beneficial effects on gut integrity improvement, inflammatory alleviation, and metabolic regulations in humans. Excess amounts of mucin and mucogenesis in the gut facilitate the development of necrotic… read more here.

Keywords: eimeria group; eimeria eimeria; group; muciniphila ... See more keywords

2'-Fucosyllactose Promotes Colonization of Akkermansia muciniphila and Prevents Colitis In Vitro and in Mice.

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Published in 2024 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.3c08305

Abstract: Akkermansia muciniphila is a potential candidate for ulcerative colitis prevention. Considering that it utilizes 2'-fucosyllactose (2'FL) for growth, 2'FL can be used to enrich the abundance of A. muciniphila in feces. However, whether the crosswalk… read more here.

Keywords: mice; muciniphila; colonization muciniphila; akkermansia muciniphila ... See more keywords

Gut microbiota: Mucin-munching bacteria modulate glucose metabolism

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Published in 2017 at "Nature Reviews Endocrinology"

DOI: 10.1038/nrendo.2016.201

Abstract: role in metabolic health, but researchers are only just determining the mechanisms underpinning this effect. In two new papers, investigators have found that Akkermansia muciniphila, a bacteria that degrades mucin in the gut lining and… read more here.

Keywords: gut; effect; glucose metabolism; gut microbiota ... See more keywords

Akkermansia muciniphila ameliorates doxorubicin-induced cardiotoxicity by regulating PPARα-dependent mitochondrial biogenesis

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Published in 2025 at "NPJ Biofilms and Microbiomes"

DOI: 10.1038/s41522-025-00712-y

Abstract: Doxorubicin (DOX) is a key chemotherapeutic agent but is also a leading cause of DOX-induced cardiotoxicity (DIC), limiting its clinical use. Akkermansia muciniphila (A. muciniphila), known for its benefits as a probiotic in treating metabolic… read more here.

Keywords: muciniphila; ameliorates doxorubicin; induced cardiotoxicity; akkermansia muciniphila ... See more keywords

Comparative effects of alive and pasteurized Akkermansia muciniphila on normal diet-fed mice

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-95738-5

Abstract: Recently, Akkermansia muciniphila an anaerobic member of the gut microbiota, has been proposed as a next-generation probiotic. The aim of this study was evaluation of the effect of alive and pasteurized A. muciniphila on health… read more here.

Keywords: normal diet; akkermansia muciniphila; alive pasteurized; pasteurized muciniphila ... See more keywords

Akkermansia muciniphila-induced trained immune phenotype increases bacterial intracellular survival and attenuates inflammation

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Published in 2024 at "Communications Biology"

DOI: 10.1038/s42003-024-05867-6

Abstract: The initial exposure to pathogens and commensals confers innate immune cells the capacity to respond distinctively upon a second stimulus. This training capacity might play key functions in developing an adequate innate immune response to… read more here.

Keywords: muciniphila; intracellular survival; bacterial intracellular; innate immune ... See more keywords

An inflammatory memory and angiogenic self-assembling nanofiber hydrogel scaffold seeded with Akkermansia muciniphila to accelerate the healing of diabetic ischemic ulcers

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Published in 2018 at "RSC Advances"

DOI: 10.1039/c8ra01662c

Abstract: Refractory ulcers are a major challenge in the treatment of a diabetic foot, because of the immunodeficient, ischemic and high-glucose microenvironment. Inflammatory memory peptides, which were extracted from the immune mediator absent in melanoma 2… read more here.

Keywords: hydrogel; diabetic ischemic; ischemic ulcers; muciniphila ... See more keywords

The role of the probiotic Akkermansia muciniphila in brain functions: insights underpinning therapeutic potential

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Published in 2022 at "Critical Reviews in Microbiology"

DOI: 10.1080/1040841x.2022.2044286

Abstract: Abstract The role of Akkermansia muciniphila, one of the most abundant microorganisms of the intestinal microbiota, has been studied extensively in metabolic diseases, such as obesity and diabetes. It is considered a next-generation probiotic microorganism.… read more here.

Keywords: akkermansia muciniphila; role; brain functions; muciniphila brain ... See more keywords

Mucin degrader Akkermansia muciniphila accelerates intestinal stem cell-mediated epithelial development

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Published in 2021 at "Gut Microbes"

DOI: 10.1080/19490976.2021.1892441

Abstract: ABSTRACT Mucin-degrading bacteria are densely populated in the intestinal epithelium; however, their interaction with intestinal stem cells (ISCs) and their progeny have not been elucidated. To determine whether mucin-degrading bacteria play a role in gut… read more here.

Keywords: mucin; akkermansia muciniphila; epithelial development; intestinal stem ... See more keywords