Structural Alterations of Mucins Are Associated with Losses in Functionality.
Sign Up to like & getrecommendations! Published in 2021 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c00073
Abstract: Commercial mucin glycoproteins are routinely used as a model to investigate the broad range of important functions mucins fulfill in our bodies, including lubrication, protection against hostile germs, and the accommodation of a healthy microbiome.… read more here.
Keywords: structural alterations; mucin; associated losses; mucins associated ... See more keywords
Mucins and associated O-glycans based immunoprofile for stratification of colorectal polyps: clinical implication for improved colon surveillance
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.12347
Abstract: Sessile serrated adenoma/polyps (SSA/P) are premalignant lesions of colorectal cancer that are difficult to distinguish histologically from hyperplastic polyps (HP) of minimal to no malignant potential. Specific markers for differentiating SSA/P from HP can aid… read more here.
Keywords: colon surveillance; mucins associated; colon; expression ... See more keywords
Mechanistic and Functional Shades of Mucins and Associated Glycans in Colon Cancer
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DOI: 10.3390/cancers12030649
Abstract: Mucus serves as the chief protective barrier against pathogenic and mechanical insults in respiratory, gastrointestinal, and urogenital tracts. Altered mucin expression, the major component of mucus, in conjunction with differential glycosylation has been strongly associated… read more here.
Keywords: mechanistic functional; mucins associated; functional shades; cancer ... See more keywords