Articles with "mucociliary dysfunction" as a keyword



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Losartan Rescues Inflammation-Related Mucociliary Dysfunction in Relevant Models of Cystic Fibrosis.

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Published in 2019 at "American journal of respiratory and critical care medicine"

DOI: 10.1164/rccm.201905-0990oc

Abstract: RATIONALE Despite therapeutic progress in treating cystic fibrosis (CF) airway disease, airway inflammation with associated mucociliary dysfunction remains largely unaddressed. Inflammation reduces the activity of apically expressed large conductance, Ca2+-activated and voltage-dependent K+ channels (BK),… read more here.

Keywords: cystic fibrosis; dysfunction; mucociliary dysfunction; inflammation ... See more keywords