Mucociliary transport, differential white blood cells, and cyto-genotoxicity in peripheral erythrocytes in fish from a polluted urban pond
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-017-0729-0
Abstract: The present study evaluated the water quality of a polluted pond through the analysis of in vitro mucociliary transport, hematological parameters, and biomarkers of cyto-genotoxicity in the Nile tilapia (Oreochromis niloticus). Blood and mucus samples… read more here.
Keywords: mucociliary transport; pond; cyto genotoxicity; blood ... See more keywords
LPS decreases CFTR open probability and mucociliary transport through generation of reactive oxygen species
Sign Up to like & getrecommendations! Published in 2021 at "Redox Biology"
DOI: 10.1016/j.redox.2021.101998
Abstract: Lipopolysaccharide (LPS) serves as the interface between gram-negative bacteria (GNB) and the innate immune response in respiratory epithelial cells (REC). Herein, we describe a novel biological role of LPS that permits GNB to persist in… read more here.
Keywords: reactive oxygen; mucociliary transport; oxygen species; open probability ... See more keywords
MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium
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DOI: 10.1126/sciadv.abq5049
Abstract: Airway mucus acts as a protective barrier and vehicle for clearance of pathogens, providing the lungs with a defense mechanism called mucociliary clearance (MCC). Airway mucus is composed of two mucins, mucin 5B (MUC5B) and… read more here.
Keywords: clearance; mucociliary transport; muc5b mobilizes; mobilizes muc5ac ... See more keywords
Mucociliary transport deficiency and disease progression in Syrian hamsters with SARS-CoV-2 infection
Sign Up to like & getrecommendations! Published in 2023 at "JCI Insight"
DOI: 10.1172/jci.insight.163962
Abstract: Substantial clinical evidence supports the notion that ciliary function in the airways is important in COVID-19 pathogenesis. Although ciliary damage has been observed in both in vitro and in vivo models, the extent or nature… read more here.
Keywords: mucociliary transport; infection; sars cov; disease progression ... See more keywords