The Dictyostelium Model for Mucolipidosis Type IV
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.741967
Abstract: Mucolipidosis type IV, a devastating neurological lysosomal disease linked to mutations in the transient receptor potential channel mucolipin 1, TRPML1, a calcium permeable channel in the membranes of vesicles in endolysosomal system. TRPML1 function is… read more here.
Keywords: dictyostelium; mucolipin; calcium; mucolipidosis type ... See more keywords
Involvement of the TRPML Mucolipin Channels in Viral Infections and Anti-viral Innate Immune Responses
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.00739
Abstract: The TRPML channels (TRPML1, TRPML2, and TRPML3), belonging to the mucolipin TRP subfamily, primary localize to a population of membrane-bonded vesicles along the endocytosis, and exocytosis pathways. Human viruses enter host cells by plasma membrane… read more here.
Keywords: mucolipin; immune responses; viral infections; role ... See more keywords