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Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23131
Abstract: Our previous research found that FOXO1 aggravates the mucosal barrier injury in inflammatory bowel disease (IBD) by regulating TLR4/MD2 signaling. In this study, we further reveal the mechanism of action whereby miRNA‐9a‐5p inhibits the mucosal…
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Keywords:
mucosal barrier;
barrier injury;
disease;
inflammatory ... See more keywords
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Published in 2018 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-018-4962-2
Abstract: BackgroundIntestinal mucosal barrier dysfunction can be caused by severe acute pancreatitis (SAP). It is normally associated with changes to mucosal autophagy and oxidative stress.ObjectiveThe aim of this study was to investigate the correlation between autophagy…
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Keywords:
mucosal barrier;
group;
oxidative stress;
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Published in 2020 at "Cell"
DOI: 10.1016/j.cell.2019.12.016
Abstract: Mucosal barrier immunity is essential for the maintenance of the commensal microflora and combating invasive bacterial infection. Although immune and epithelial cells are thought to be the canonical orchestrators of this complex equilibrium, here, we…
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Keywords:
immunity;
nervous system;
mucosal barrier;
enteric nervous ... See more keywords
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Published in 2018 at "Fitoterapia"
DOI: 10.1016/j.fitote.2017.11.012
Abstract: Insulin-like growth factor I (IGF-I) and binding protein 3 (IGFBP-3) play a role in the maintenance of gut mucosal barrier function. Nevertheless, IGF-I/IGFBP-3 and tight junction protein (TJP) expression in small intestinal mucosa are often…
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Keywords:
igfbp signaling;
acute endotoxemia;
igf;
mucosal barrier ... See more keywords
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Published in 2020 at "British Journal of Nutrition"
DOI: 10.1017/s000711451900285x
Abstract: Abstract Both konjac glucomannan (KGM) and inulin oligosaccharide have been shown to improve bowel function, but their effects on the mucosal barrier function and immunity are not fully understood. The aim of the present study…
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Keywords:
mucosal barrier;
barrier function;
immunity;
inulin oligosaccharide ... See more keywords
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Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c08564
Abstract: The pharmacological values of marine algal polysaccharides on gut health are being recognized in recent research. However, the protective effect of degraded polysaccharides from Porphyra haitanensis (PHP-D) on the colonic mucosal barrier damaged in ulcerative…
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Keywords:
mucosal barrier;
gut microbiota;
colitis;
dextran sulfate ... See more keywords
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Published in 2018 at "International Journal of Obesity"
DOI: 10.1038/s41366-018-0125-y
Abstract: Background/ObjectivesObesity is an independent risk factor for severe acute pancreatitis (AP). Leptin plays an important role in energy homeostasis. It has been reported that leptin might also participate in the regulation of the intestinal mucosal…
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Keywords:
acute pancreatitis;
leptin;
intestinal mucosal;
mucosal barrier ... See more keywords
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Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-018-36266-7
Abstract: Obesity may aggravate acute pancreatitis (AP) through damaging the intestinal mucosal barrier (IMB). The underlying mechanism remains unclear. This study was aimed to provide further data to clarify the mechanism. 48 rats were divided into…
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Keywords:
acute pancreatitis;
fed rats;
intestinal mucosal;
mucosal barrier ... See more keywords
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Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-021-03787-7
Abstract: GPR120 (encoded by FFAR4 gene) is a receptor for long chain fatty acids, activated by ω-3 Polyunsaturated Fatty Acids (PUFAs), and expressed in many cell types. Its role in the context of colorectal cancer (CRC)…
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Keywords:
mucosal barrier;
gpr120;
barrier integrity;
progression ... See more keywords
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Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2047405
Abstract: ABSTRACT Intestinal barrier dysfunction is inflammatory bowel disease’s hallmark. Berberine (BBR) has manifested its anti-inflammatory properties in colitis. For exploring the molecular mechanism of BBR’s impacts on colitis, application of a dextran sodium sulfate-induced mouse…
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Keywords:
mucosal barrier;
barrier;
mir 103a;
colitis ... See more keywords
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Published in 2022 at "Pancreas"
DOI: 10.1097/mpa.0000000000002169
Abstract: Objectives The purpose of this study was to investigate the role and mechanism of toll-like receptor 9 (TLR9) in intestinal mucosal barrier injury in mice with severe acute pancreatitis (SAP). Methods The mice were randomly…
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Keywords:
mucosal barrier;
toll like;
intestinal mucosal;
mice ... See more keywords