Preclinical assessment of transplantable human nasal mucosal epithelial cell sheets
Sign Up to like & getrecommendations! Published in 2021 at "Regenerative Therapy"
DOI: 10.1016/j.reth.2021.03.006
Abstract: Introduction We previously reported a new cell transplantation therapy for patients with intractable otitis media using autologous nasal mucosal epithelial cell sheets, manufactured using temperature-responsive cell culture inserts. The current study aimed to verify whether… read more here.
Keywords: cell sheets; nasal mucosal; human nasal; mucosal epithelial ... See more keywords
Tissue Harvesting Site and Culture Medium Affect Attachment, Growth, and Phenotype of Ex Vivo Expanded Oral Mucosal Epithelial Cells
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DOI: 10.1038/s41598-017-00417-z
Abstract: Transplantation of cultured oral mucosal epithelial cells (OMECs) is a promising treatment strategy for limbal stem cell deficiency. In order to improve the culture method, we investigated the effects of four culture media and tissue… read more here.
Keywords: growth; medium; oral mucosal; mucosal epithelial ... See more keywords
Interferon Regulatory Factor 4 (IRF4) Promotes Lipopolysaccharide-Induced Colonic Mucosal Epithelial Cell Proliferation by Regulating Macrophage Polarization
Sign Up to like & getrecommendations! Published in 2022 at "European Surgical Research"
DOI: 10.1159/000525753
Abstract: Introduction: Ulcerative colitis (UC) is a chronic disease characterized by diffuse inflammation of the mucosa of colon and rectum. Interferon regulatory factor 4 (IRF4) mediates macrophage anti-inflammatory phenotype (alternatively activated macrophages [M2]). This study aimed… read more here.
Keywords: irf4; mucosal epithelial; cell; proliferation ... See more keywords
Atractylodes-I overcomes the oxidative stress-induced colonic mucosal epithelial cells dysfunction to prevent irritable bowel syndrome via modulating the miR-34a-5p-LDHA signaling pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Current molecular medicine"
DOI: 10.2174/1566524022666220811161111
Abstract: BACKGROUND Irritable bowel syndrome (IBS) is a known brain-gut disorder. Currently, the molecular and cellular mechanisms of IBS remain unclear. Atractylenolide-I (ATL-I) is majorly bioactive component extracted from Rhizoma Atractylodes Macrocephalae. METHODS Studies have revealed… read more here.
Keywords: mucosal epithelial; oxidative stress; colonic mucosal; mucosal ... See more keywords
Antimicrobial Effect of Extracellular Vesicles Derived From Human Oral Mucosal Epithelial Cells on Candida albicans
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.777613
Abstract: Candida albicans (C. albicans) is a commensal microorganism that colonizes the mucosal surfaces of healthy individuals. Changes in the host or environment can lead to overgrowth of C. albicans and infection of the host. Extracellular… read more here.
Keywords: mucosal epithelial; oral mucosal; leuk evs; microscopy ... See more keywords
Early Clinical Outcomes of the First Commercialized Human Autologous Ex Vivo Cultivated Oral Mucosal Epithelial Cell Transplantation for Limbal Stem Cell Deficiency: Two Case Reports and Literature Review
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24108926
Abstract: The first product in the world for ex vivo cultivated oral mucosal epithelial cell transplantation (COMET) to treat limbal stem cell deficiency (LSCD), named Ocural®, was launched in June 2021 in Japan. COMET was performed… read more here.
Keywords: mucosal epithelial; cell; epithelial cell; oral mucosal ... See more keywords