Specific microbiota enhances intestinal IgA levels by inducing TGF‐β in T follicular helper cells of Peyer's patches in mice
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DOI: 10.1002/eji.201948474
Abstract: In humans and mice, mucosal immune responses are dominated by IgA antibodies and the cytokine TGF‐β, suppressing unwanted immune reactions but also targeting Ig class switching to IgA. It had been suggested that eosinophils promote… read more here.
Keywords: iga levels; intestinal iga; microbiota; iga ... See more keywords
Detection of Anti‐SARS‐CoV‐2 Mucosal Immunoglobulin A in Clinical Saliva Samples After a Dose of Novavax COVID‐19 Vaccine
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DOI: 10.1002/jmv.70645
Abstract: Immunoglobulin (Ig) A acts as a first line of defense against respiratory pathogens. Mucosal IgA in salivary and nasal passages has a rapid response to antigens and can play a protective role against reinfection. The… read more here.
Keywords: sars cov; anti sars; detection; mucosal iga ... See more keywords
#1286 Dextran sulfate sodium-induced colitis causes production of degalactosylated mucosal IgA and glomerular IgA-IgG deposition in HIGA mice
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DOI: 10.1093/ndt/gfaf116.1097
Abstract: IgA nephropathy (IgAN) is the most common form of glomerulonephritis. IgAN is exacerbated after upper respiratory tract inflammation and enteritis and associated with chronic inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis. There… read more here.
Keywords: mice; iga; mucosal iga; deposition ... See more keywords