Candidate therapeutic agents in a newly established triple wild‐type mucosal melanoma cell line
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DOI: 10.1002/cac2.12315
Abstract: Mucosal melanoma has characteristically distinct genetic features and typically poor prognosis. The lack of representative mucosal melanoma models, especially cell lines, has hindered translational research on this melanoma subtype. In this study, we aimed to… read more here.
Keywords: mucosal melanoma; melanoma cell; cell line; melanoma ... See more keywords
Approaches to regional lymph node metastasis in patients with head and neck mucosal melanoma
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DOI: 10.1002/cncr.31083
Abstract: Mucosal melanomas in the head and neck region are most often located in the nasal cavity and paranasal sinuses. To the authors' knowledge, the prognostic effects of lymph node metastasis in patients with sinonasal mucosal… read more here.
Keywords: node metastasis; mucosal melanoma; lymph node; metastasis patients ... See more keywords
Intralesional interleukin-2 for unresectable mucosal melanoma refractory to nivolumab
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-017-2012-0
Abstract: 13, 17). Despite the lack of PD-L1 expression, we initiated systemic treatment with nivolumab at 3 mg/kg body weight biweekly. The tumor was initially stable in size but progressed in the further disease course (Fig.… read more here.
Keywords: melanoma; mucosal melanoma; treatment; interleukin unresectable ... See more keywords
Current concepts in advanced sinonasal mucosal melanoma: a single institution experience
Sign Up to like & getrecommendations! Published in 2019 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-019-05458-w
Abstract: PurposeTo present outcome measures of sinonasal mucosal melanoma (SMM) patients with particular focus on current radiological and therapeutic options, especially in the non-curative setting (immunotherapy).MethodsRetrospective study on SMM patients treated at our institution between January… read more here.
Keywords: mucosal melanoma; institution; patients treated; sinonasal mucosal ... See more keywords
Analysis of TSC1 mutation spectrum in mucosal melanoma
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DOI: 10.1007/s00432-017-2550-z
Abstract: PurposeMucosal melanoma is a relatively rare subtype of melanoma for which no clearly established therapeutic strategy exists. The genes of the mTOR signalling pathway have drawn great attention as key targets for cancer treatment, including… read more here.
Keywords: melanoma; mucosal melanoma; mutation; tsc1 mutations ... See more keywords
Rh-endostatin combined with chemotherapy in patients with advanced or recurrent mucosal melanoma: retrospective analysis of real-world data
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DOI: 10.1007/s10637-021-01172-9
Abstract: Background. Mucosal melanoma is rare and has distinct clinical and genetic features. Even with advances in targeted and immune therapies, the survival of patients with advanced or recurrent mucosal melanomas remains poor. The standard treatment… read more here.
Keywords: endostatin; mucosal melanoma; mucosal; recurrent mucosal ... See more keywords
Ki-67 and p53 expression in head and neck mucosal melanoma: A clinicopathologic analysis of predictors of outcome.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2021.151789
Abstract: OBJECTIVE To explore the prognostic value of Ki-67 and p53 in patients with head and neck mucosal melanoma by analyzing the relevant data from previous patients. METHODS Data on Ki-67 and p53 immunohistochemical staining in… read more here.
Keywords: mucosal melanoma; neck mucosal; expression; p53 expression ... See more keywords
Mucosal Melanoma.
Sign Up to like & getrecommendations! Published in 2021 at "Clinics in plastic surgery"
DOI: 10.1016/j.cps.2021.05.010
Abstract: Mucosal melanoma is a rare but aggressive cancer arising in mucosal surfaces most commonly in the head and neck. The clinical presentation is often nonspecific and differs in relation to the site of origin so… read more here.
Keywords: mucosal melanoma; mucosal;
Mucosal melanoma of the head and neck.
Sign Up to like & getrecommendations! Published in 2017 at "Critical reviews in oncology/hematology"
DOI: 10.1016/j.critrevonc.2017.01.019
Abstract: Mucosal melanoma of the head and neck is a very rare and aggressive malignancy with a very poor prognosis. The nasal cavity, paranasal sinuses, and oral cavity are the most common locations. One-, 3- and… read more here.
Keywords: mucosal melanoma; melanoma head; head neck; mucosal ... See more keywords
Real-world efficacy and safety of axitinib in combination with anti-programmed cell death-1 antibody for advanced mucosal melanoma.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of cancer"
DOI: 10.1016/j.ejca.2021.07.018
Abstract: PURPOSE The combination of vascular endothelial growth factor receptor (VEGFR) inhibitor and programmed cell death-1 (PD-1) blockade provides promising therapeutic opportunities for advanced mucosal melanoma in early phase trials. The aim of this retrospective study… read more here.
Keywords: combination; mucosal melanoma; advanced mucosal; efficacy safety ... See more keywords
Loss-of-function variants in FSIP1 identified by targeted sequencing are associated with one particular subtype of mucosal melanoma
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DOI: 10.1016/j.gene.2020.144964
Abstract: Abstract Background Mucosal melanoma is a tumor caused by the malignant transformation of pigment-producing cells and can arise from any mucosal tissue where melanocytes are present. Due to its rarity, the mucosal melanoma subtype is… read more here.
Keywords: loss; mucosal melanoma; targeted sequencing; gene ... See more keywords