Articles with "mucosal vaccine" as a keyword



Kinetics of IgA Subtypes and Cytokines in Respiratory Secretions Following Immunization With COVID‐19 Mucosal Vaccine

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Published in 2025 at "Journal of Medical Virology"

DOI: 10.1002/jmv.70638

Abstract: The COVID‐19 pandemic highlights the need for mucosal vaccines inducing respiratory secretory IgA (sIgA), as traditional intramuscular vaccines primarily elicit systemic IgG with limited mucosal protection. This study systematically compared mucosal immune responses induced by… read more here.

Keywords: mucosal; immunization; mucosal vaccine; covid mucosal ... See more keywords

Mucosal Vaccine Delivery Using Mucoadhesive Polymer Particulate Systems

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Published in 2021 at "Tissue Engineering and Regenerative Medicine"

DOI: 10.1007/s13770-021-00373-w

Abstract: Vaccination has been recently attracted as one of the most successful medical treatments of the prevalence of many infectious diseases. Mucosal vaccination has been interested in many researchers because mucosal immune responses play part in… read more here.

Keywords: polymeric particles; vaccine delivery; delivery; mucosal vaccine ... See more keywords

Development and pre-clinical evaluation in the swine model of a mucosal vaccine tablet for human influenza viruses: A proof-of-concept study.

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Published in 2018 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2018.01.021

Abstract: Liquid vaccine formulations present some disadvantages such as stability problems, cold chain requirement or administration by trained personnel. Vaccine formulated as tablets would present a wide range of progress such as an increase stability that… read more here.

Keywords: human influenza; influenza viruses; swine model; influenza ... See more keywords

Enhanced protection against FMDV in cattle after prime- boost vaccination based on mucosal and inactivated FMD vaccine.

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Published in 2017 at "Veterinary microbiology"

DOI: 10.1016/j.vetmic.2017.08.014

Abstract: Improved immunization and control strategies and platforms are greatly needed for foot and mouth disease virus (FMDV) and mucosal vaccines propose an effective strategy for the control FMDV by blocking viral entry. In this study,… read more here.

Keywords: protection; mucosal; inactivated fmd; mucosal vaccine ... See more keywords

Development of an anti-tauopathy mucosal vaccine specifically targeting pathologic conformers

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Published in 2024 at "NPJ Vaccines"

DOI: 10.1038/s41541-024-00904-1

Abstract: Alzheimer’s disease (AD) and related tauopathies are associated with pathological tau protein aggregation, which plays an important role in neurofibrillary degeneration and dementia. Targeted immunotherapy to eliminate pathological tau aggregates is known to improve cognitive… read more here.

Keywords: taurd; mucosal vaccine; pathological tau; tau ... See more keywords
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High-Resolution Quantitative Mapping of Macaque Cervicovaginal Epithelial Thickness: Implications for Mucosal Vaccine Delivery

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Published in 2021 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2021.660524

Abstract: Vaginal mucosal surfaces naturally offer some protection against sexually transmitted infections (STIs) including Human Immunodeficiency Virus-1, however topical preventative medications or vaccine designed to boost local immune responses can further enhance this protection. We previously… read more here.

Keywords: high resolution; mucosal; mucosal vaccine; vaginal mucosal ... See more keywords

Surface Display of porcine circovirus type 2 antigen protein cap on the spores of bacillus subtilis 168: An effective mucosal vaccine candidate

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1007202

Abstract: The oral mucosal vaccine has great potential in preventing a series of diseases caused by porcine circovirus type 2 (PCV2) infection. This study constructed a recombinant Bacillus subtilis RB with PCV2 Capsid protein (Cap) on… read more here.

Keywords: protein cap; circovirus type; bacillus subtilis; mucosal vaccine ... See more keywords

Research progress in the development of natural-product-based mucosal vaccine adjuvants

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1152855

Abstract: Mucosal vaccines have great potential and advantages in preventing infection caused by multiple pathogens. In developing mucosal vaccines, the biggest challenge comes from finding safe and effective adjuvants and drug delivery systems. Great progress has… read more here.

Keywords: progress; mucosal vaccine; product based; vaccine adjuvants ... See more keywords

Rapid and Highly Efficient Genetic Transformation and Application of Interleukin-17B Expressed in Duckweed as Mucosal Vaccine Adjuvant

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Published in 2022 at "Biomolecules"

DOI: 10.3390/biom12121881

Abstract: Molecular farming utilizes plants as a platform for producing recombinant biopharmaceuticals. Duckweed, the smallest and fastest growing aquatic plant, is a promising candidate for molecular farming. However, the efficiency of current transformation methods is generally… read more here.

Keywords: interleukin 17b; mucosal vaccine; chil 17b; duckweed ... See more keywords