Vocal fold mucus layer: Comparison of histological protocols for visualization in mice
Sign Up to like & getrecommendations! Published in 2022 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.743
Abstract: The epithelial associated mucus layer of vocal fold (VF) mucosa, plays an essential role in protecting and lubricating the tissue, as well as promoting normal voice quality. Serving as a habitat for laryngeal microbiota involved… read more here.
Keywords: layer comparison; vocal fold; fold mucus; mucus ... See more keywords
Prebiotic protects against anatase titanium dioxide nanoparticles-induced microbiota-mediated colonic barrier defects
Sign Up to like & getrecommendations! Published in 2019 at "NanoImpact"
DOI: 10.1016/j.impact.2019.100164
Abstract: Abstract Ingestion of engineered nanoparticles (NPs) can affect gut microbiota composition, and gut bacteria influences colonic epithelial function. The colonic mucus layer is a physical barrier that separates trillions of gut bacteria from the host… read more here.
Keywords: mucus layer; tio2 nps; colonic barrier; barrier ... See more keywords
Virus-Mimicking Mesoporous Silica Nanoparticles with an Electrically Neutral and Hydrophilic Surface to Improve the Oral Absorption of Insulin by Breaking Through Dual Barriers of the Mucus Layer and the Intestinal Epithelium.
Sign Up to like & getrecommendations! Published in 2021 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c00580
Abstract: Protein and peptide drugs orally suffer from extremely low bioavailability principally for the complicated gastrointestinal environment along with the difficulty of passing through the mucus layer and the underlying epithelium. In our work, we fabricated… read more here.
Keywords: insulin; mucus layer; msn nh2; epithelium ... See more keywords
Relationship between mucosa-associated gut microbiota and human diseases
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical Society Transactions"
DOI: 10.1042/bst20201201
Abstract: The mucus layer covering the gastrointestinal (GI) tract plays a critical role in maintaining gut homeostasis. In the colon, the inner mucus layer ensures commensal microbes are kept at a safe distance from the epithelium… read more here.
Keywords: microbiota; human diseases; associated gut; relationship mucosa ... See more keywords
Effects of thermal airflow and mucus-layer interaction on hygroscopic droplet deposition in a simple mouth–throat model
Sign Up to like & getrecommendations! Published in 2018 at "Aerosol Science and Technology"
DOI: 10.1080/02786826.2018.1476751
Abstract: Abstract Hygroscopic growth of inhaled aerosols plays an important role in determining particle trajectories and hence local deposition sites. Accurate predictions of airway temperature and humidity as well as droplet–vapor interaction are critical for the… read more here.
Keywords: mucus layer; layer; interaction; mucus ... See more keywords
How microbial glycosyl hydrolase activity in the gut mucosa initiates microbial cross-feeding
Sign Up to like & getrecommendations! Published in 2021 at "Glycobiology"
DOI: 10.1093/glycob/cwab105
Abstract: Abstract The intestinal epithelium is protected from direct contact with gut microbes by a mucus layer. This mucus layer consists of secreted mucin glycoproteins. The outer mucus layer in the large intestine forms a niche… read more here.
Keywords: microbial cross; mucus layer; gut; cross feeding ... See more keywords
Interaction between mucus layer and gut microbiota in NAFLD: Soil and seeds.
Sign Up to like & getrecommendations! Published in 2023 at "Chinese medical journal"
DOI: 10.1097/cm9.0000000000002711
Abstract: ABSTRACT The intestinal mucus layer is a barrier that separates intestinal contents and epithelial cells, as well as acts as the "mucus layer-soil" for intestinal flora adhesion and colonization. Its structural and functional integrity is… read more here.
Keywords: gut; seed; mucus; mucus layer ... See more keywords
Muc2-dependent microbial colonization of the jejunal mucus layer is diet sensitive and confers local resistance to enteric pathogen infection.
Sign Up to like & getrecommendations! Published in 2023 at "Cell reports"
DOI: 10.2139/ssrn.3931635
Abstract: Intestinal mucus barriers normally prevent microbial infections but are sensitive to diet-dependent changes in the luminal environment. Here we demonstrate that mice fed a Western-style diet (WSD) suffer regiospecific failure of the mucus barrier in… read more here.
Keywords: colonization; jejunal mucus; mucus; mucus layer ... See more keywords
Reprogrammed fecal and mucosa-associated intestinal microbiota and weakened mucus layer in intestinal goblet cell- specific Piezo1-deficient mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.1035386
Abstract: Dysfunction of the mucus layer allows commensal and pathogenic microorganisms to reach the intestinal epithelium, thereby leading to infection and inflammation. This barrier is synthesized and secreted by host goblet cells. Many factors that influence… read more here.
Keywords: microbiota; goblet; mucosa associated; mucus layer ... See more keywords
Mimicking the Intestinal Host–Pathogen Interactions in a 3D In Vitro Model: The Role of the Mucus Layer
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14081552
Abstract: The intestinal mucus lines the luminal surface of the intestinal epithelium. This mucus is a dynamic semipermeable barrier and one of the first-line defense mechanisms against the outside environment, protecting the body against chemical, mechanical,… read more here.
Keywords: pathogen interactions; mucus layer; mucus; host pathogen ... See more keywords