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   Articles with "mucus layer" as a keyword



Vocal fold mucus layer: Comparison of histological protocols for visualization in mice

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recommendations! Published in 2022 at "Laryngoscope Investigative Otolaryngology"

DOI: 10.1002/lio2.743

Abstract: The epithelial associated mucus layer of vocal fold (VF) mucosa, plays an essential role in protecting and lubricating the tissue, as well as promoting normal voice quality. Serving as a habitat for laryngeal microbiota involved… read more here.

Keywords: layer comparison; vocal fold; fold mucus; mucus ... See more keywords

Characterizing interregional differences in the rheological properties and composition of rat small intestinal mucus

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recommendations! Published in 2024 at "Drug Delivery and Translational Research"

DOI: 10.1007/s13346-024-01574-1

Abstract: The mucus layer in the small intestine is generally regarded as a barrier to drug absorption. However, the mucus layer is a complex system, and presently, only a few studies have been conducted to elucidate… read more here.

Keywords: small intestine; mucus; rheological properties; rat small ... See more keywords

Prebiotic protects against anatase titanium dioxide nanoparticles-induced microbiota-mediated colonic barrier defects

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recommendations! Published in 2019 at "NanoImpact"

DOI: 10.1016/j.impact.2019.100164

Abstract: Abstract Ingestion of engineered nanoparticles (NPs) can affect gut microbiota composition, and gut bacteria influences colonic epithelial function. The colonic mucus layer is a physical barrier that separates trillions of gut bacteria from the host… read more here.

Keywords: mucus layer; tio2 nps; colonic barrier; barrier ... See more keywords

Virus-Mimicking Mesoporous Silica Nanoparticles with an Electrically Neutral and Hydrophilic Surface to Improve the Oral Absorption of Insulin by Breaking Through Dual Barriers of the Mucus Layer and the Intestinal Epithelium.

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recommendations! Published in 2021 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.1c00580

Abstract: Protein and peptide drugs orally suffer from extremely low bioavailability principally for the complicated gastrointestinal environment along with the difficulty of passing through the mucus layer and the underlying epithelium. In our work, we fabricated… read more here.

Keywords: insulin; mucus layer; msn nh2; epithelium ... See more keywords

Relationship between mucosa-associated gut microbiota and human diseases

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recommendations! Published in 2022 at "Biochemical Society Transactions"

DOI: 10.1042/bst20201201

Abstract: The mucus layer covering the gastrointestinal (GI) tract plays a critical role in maintaining gut homeostasis. In the colon, the inner mucus layer ensures commensal microbes are kept at a safe distance from the epithelium… read more here.

Keywords: microbiota; human diseases; associated gut; relationship mucosa ... See more keywords

Effects of thermal airflow and mucus-layer interaction on hygroscopic droplet deposition in a simple mouth–throat model

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recommendations! Published in 2018 at "Aerosol Science and Technology"

DOI: 10.1080/02786826.2018.1476751

Abstract: Abstract Hygroscopic growth of inhaled aerosols plays an important role in determining particle trajectories and hence local deposition sites. Accurate predictions of airway temperature and humidity as well as droplet–vapor interaction are critical for the… read more here.

Keywords: mucus layer; layer; interaction; mucus ... See more keywords

Development of a Caco-2-based intestinal mucosal model to study intestinal barrier properties and bacteria–mucus interactions

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recommendations! Published in 2024 at "Gut Microbes"

DOI: 10.1080/19490976.2024.2434685

Abstract: ABSTRACT The intestinal mucosal barrier is a dynamic system that allows nutrient uptake, stimulates healthy microbe–host interactions, and prevents invasion by pathogens. The mucosa consists of epithelial cells connected by cellular junctions that regulate the… read more here.

Keywords: intestinal mucosal; caco; culture; mucus ... See more keywords

How microbial glycosyl hydrolase activity in the gut mucosa initiates microbial cross-feeding

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recommendations! Published in 2021 at "Glycobiology"

DOI: 10.1093/glycob/cwab105

Abstract: Abstract The intestinal epithelium is protected from direct contact with gut microbes by a mucus layer. This mucus layer consists of secreted mucin glycoproteins. The outer mucus layer in the large intestine forms a niche… read more here.

Keywords: microbial cross; mucus layer; gut; cross feeding ... See more keywords

Interaction between mucus layer and gut microbiota in NAFLD: Soil and seeds.

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recommendations! Published in 2023 at "Chinese medical journal"

DOI: 10.1097/cm9.0000000000002711

Abstract: ABSTRACT The intestinal mucus layer is a barrier that separates intestinal contents and epithelial cells, as well as acts as the "mucus layer-soil" for intestinal flora adhesion and colonization. Its structural and functional integrity is… read more here.

Keywords: gut; seed; mucus; mucus layer ... See more keywords

Peptidoglycan-Chi3l1 interaction shapes gut microbiota in intestinal mucus layer

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recommendations! Published in 2024 at "eLife"

DOI: 10.1101/2023.10.03.560754

Abstract: The balanced gut microbiota in intestinal mucus layer plays an instrumental role in the health of the host. However, the mechanisms by which the host regulates microbial communities in the mucus layer remain largely unknown.… read more here.

Keywords: chi3l1; interaction; gut microbiota; mucus layer ... See more keywords

Artificial mucus layer formed in response to ROS for the oral treatment of inflammatory bowel disease.

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recommendations! Published in 2024 at "Science advances"

DOI: 10.1126/sciadv.ado8222

Abstract: The artificial mucus layer, such as hydrogels, used to repair the damaged intestinal barrier, is a promising treatment for inflammatory bowel disease (IBD). However, the currently reported hydrogel-based artificial barriers are administered via rectal injection,… read more here.

Keywords: mucus; mucus layer; treatment inflammatory; artificial mucus ... See more keywords