Articles with "mucus plug" as a keyword



Mucus Plugs Persist in Asthma and Changes in Mucus Plugs Associate with Changes in Airflow Over Time.

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Published in 2022 at "American journal of respiratory and critical care medicine"

DOI: 10.1164/rccm.202110-2265oc

Abstract: RATIONALE Cross-sectional analysis of mucus plugs in computed tomography (CT) lung scans in the Severe Asthma Research Program (SARP)-3 showed a high mucus plug phenotype. OBJECTIVES To determine if mucus plugs are a persistent asthma… read more here.

Keywords: time; mucus plug; mucus; changes mucus ... See more keywords

Effect of Dupilumab on Mucus Burden in Patients with Moderate-to-Severe Asthma: The VESTIGE Trial.

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Published in 2025 at "American journal of respiratory and critical care medicine"

DOI: 10.1164/rccm.202410-1894oc

Abstract: RATIONALE Chronic mucus hypersecretion contributes to airway obstruction in asthma. OBJECTIVES Assess dupilumab efficacy by baseline mucus plug score. METHODS In VESTIGE (NCT04400318), adults with moderate-to-severe asthma, baseline blood eosinophils ≥300 cells/μL, and fractional exhaled… read more here.

Keywords: moderate severe; plug score; mucus plug; mucus ... See more keywords

Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction

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Published in 2018 at "Journal of Clinical Investigation"

DOI: 10.1172/jci95693

Abstract: BACKGROUND. The link between mucus plugs and airflow obstruction has not been established in chronic severe asthma, and the role of eosinophils and their products in mucus plug formation is unknown. METHODS. In clinical studies,… read more here.

Keywords: airflow obstruction; mucus plugs; mucus plug; mucus ... See more keywords

Mucus Plug Removed Using Bronchoscopy with a Cryoprobe

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Published in 2022 at "Internal Medicine"

DOI: 10.2169/internalmedicine.9657-22

Abstract: A 43-year-old woman with a history of asthma presented to our hospital with dyspnea. A laboratory examination revealed peripheral eosinophilia (1,605/μL) and hyperimmunoglobulinemia E (2,609 mg/dL). Computed tomography revealed high-attenuation mucus in the right hilar… read more here.

Keywords: mucus plug; plug removed; mucus; picture ... See more keywords