Airway microbiota in children with bronchial mucus plugs caused by Mycoplasma pneumoniae pneumonia.
Sign Up to like & getrecommendations! Published in 2020 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2020.105902
Abstract: BACKGROUND There is increasing evidence for a role of lung microbiota in the pathogenesis of Mycoplasma pneumoniae pneumonia (MPP). However, the alterations of lung microbiota in MPP with bronchial mucus plugs and its role in… read more here.
Keywords: bronchial mucus; mucus plugs; mpp children; mucus ... See more keywords
Computed tomography mucus plugs and airway tree structure in patients with chronic obstructive pulmonary disease: Associations with airflow limitation, health‐related independence and mortality
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DOI: 10.1111/resp.14776
Abstract: Mucus plugs and underlying airway tree structure can affect airflow limitation and prognosis in patients with chronic obstructive pulmonary disease (COPD), but their relative roles are unclear. This study used two COPD cohorts to examine… read more here.
Keywords: mucus plugs; airway tree; airflow limitation; tree structure ... See more keywords
Mucus Plugs Persist in Asthma and Changes in Mucus Plugs Associate with Changes in Airflow Over Time.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.202110-2265oc
Abstract: RATIONALE Cross-sectional analysis of mucus plugs in computed tomography (CT) lung scans in the Severe Asthma Research Program (SARP)-3 showed a high mucus plug phenotype. OBJECTIVES To determine if mucus plugs are a persistent asthma… read more here.
Keywords: time; mucus plug; mucus; changes mucus ... See more keywords
Airway Mucus Plugs on Chest Computed Tomography Are Associated with Exacerbations in COPD.
Sign Up to like & getrecommendations! Published in 2024 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.202403-0632oc
Abstract: Rationale/Objective: Acute exacerbations (AEs) of chronic obstructive pulmonary disease (COPD) are associated with significant morbidity and mortality. Whether mucus plugs are associated with prospective exacerbations has not been examined extensively. METHODS Mucus plugs were visually-identified… read more here.
Keywords: chest computed; mucus; mucus plugs; plugs associated ... See more keywords
Mucus Plugs Correlate with Small Airway Remodelling in Asthma: A Case-Control Study.
Sign Up to like & getrecommendations! Published in 2025 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.202501-0310oc
Abstract: RATIONALE The observation that mucus plugs in proximal airways on computed tomography (CT) correlate with disease severity and airflow obstruction has highlighted their role in asthma. Due to the resolution of CT, it is unknown… read more here.
Keywords: small airway; airway remodelling; mucus; mucus plugs ... See more keywords
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction
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DOI: 10.1172/jci95693
Abstract: BACKGROUND. The link between mucus plugs and airflow obstruction has not been established in chronic severe asthma, and the role of eosinophils and their products in mucus plug formation is unknown. METHODS. In clinical studies,… read more here.
Keywords: airflow obstruction; mucus plugs; mucus plug; mucus ... See more keywords
Novel imaging phenotypes of naïve asthma patients with distinctive clinical characteristics and T2 inflammation traits
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic Advances in Chronic Disease"
DOI: 10.1177/20406223221084831
Abstract: Objective: This study aims to describe the imaging features of naïve asthma patients, defined as not receiving corticosteroids or other asthma medications for at least 1 month, and their association with therapeutic response, and to… read more here.
Keywords: asthma patients; inflammation; imaging phenotypes; airway remodeling ... See more keywords
Automated computed tomographic analysis of bronchial thickness and mucus plugs in bronchiectasis with asthma
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DOI: 10.1183/23120541.00736-2024
Abstract: Background Bronchiectasis disease is characterised by cough, sputum and exacerbations, with chest computed tomography (CT) typically showing bronchial wall thickening and mucus plugging in addition to bronchial dilation. Asthma is a common comorbidity and associated… read more here.
Keywords: mucus plugs; bronchiectasis; thickness; bronchial wall ... See more keywords
Mucus plugs in the airways of asthmatic subjects and smoking status
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DOI: 10.1186/s12931-024-02665-w
Abstract: Background Mucus plugs have been described in the airways of asthmatic subjects, particularly those with associated with type 2 inflammation and sputum eosinophilia. In the current study we addressed the question of whether smoking, neutrophilic… read more here.
Keywords: mucus score; mucus; mucus plugs; smoking status ... See more keywords
Risk factors analysis of airway mucus plugs in community-acquired refractory mycoplasma pneumoniae pneumonia: a case-control study
Sign Up to like & getrecommendations! Published in 2025 at "Italian Journal of Pediatrics"
DOI: 10.1186/s13052-025-02071-y
Abstract: To analyze the clinical characteristics and explore the risk factors for airway mucus plugs in children with community-acquired refractory Mycoplasma pneumoniae pneumonia (ca-RMPP). A retrospective study was conducted on hospitalized children diagnosed with ca-RMPP from… read more here.
Keywords: mucus plugs; plugs group; airway mucus; risk factors ... See more keywords
Changes in airway diameter and mucus plugs in patients with asthma exacerbation
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DOI: 10.1371/journal.pone.0229238
Abstract: Background Airway obstruction due to decreased airway diameter and increased incidence of mucus plugs has not been directly observed in asthma exacerbation. We studied the changes in the inner diameter of the airway (Din) and… read more here.
Keywords: mucus plugs; airway diameter; patients asthma; asthma exacerbation ... See more keywords