Airway microbiota in children with bronchial mucus plugs caused by Mycoplasma pneumoniae pneumonia.
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DOI: 10.1016/j.rmed.2020.105902
Abstract: BACKGROUND There is increasing evidence for a role of lung microbiota in the pathogenesis of Mycoplasma pneumoniae pneumonia (MPP). However, the alterations of lung microbiota in MPP with bronchial mucus plugs and its role in… read more here.
Keywords: bronchial mucus; mucus plugs; mpp children; mucus ... See more keywords
Mucus Plugs Persist in Asthma and Changes in Mucus Plugs Associate with Changes in Airflow Over Time.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.202110-2265oc
Abstract: RATIONALE Cross-sectional analysis of mucus plugs in computed tomography (CT) lung scans in the Severe Asthma Research Program (SARP)-3 showed a high mucus plug phenotype. OBJECTIVES To determine if mucus plugs are a persistent asthma… read more here.
Keywords: time; mucus plug; mucus; changes mucus ... See more keywords
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction
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DOI: 10.1172/jci95693
Abstract: BACKGROUND. The link between mucus plugs and airflow obstruction has not been established in chronic severe asthma, and the role of eosinophils and their products in mucus plug formation is unknown. METHODS. In clinical studies,… read more here.
Keywords: airflow obstruction; mucus plugs; mucus plug; mucus ... See more keywords
Novel imaging phenotypes of naïve asthma patients with distinctive clinical characteristics and T2 inflammation traits
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DOI: 10.1177/20406223221084831
Abstract: Objective: This study aims to describe the imaging features of naïve asthma patients, defined as not receiving corticosteroids or other asthma medications for at least 1 month, and their association with therapeutic response, and to… read more here.
Keywords: asthma patients; inflammation; imaging phenotypes; airway remodeling ... See more keywords
Changes in airway diameter and mucus plugs in patients with asthma exacerbation
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DOI: 10.1371/journal.pone.0229238
Abstract: Background Airway obstruction due to decreased airway diameter and increased incidence of mucus plugs has not been directly observed in asthma exacerbation. We studied the changes in the inner diameter of the airway (Din) and… read more here.
Keywords: mucus plugs; airway diameter; patients asthma; asthma exacerbation ... See more keywords
Autopsy and Imaging Studies of Mucus in Asthma. Lessons Learned about Disease Mechanisms and the Role of Mucus in Airflow Obstruction
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DOI: 10.1513/annalsats.201807-485aw
Abstract: &NA; Autopsy studies in fatal asthma have clearly documented the central role of airway plugging with pathologic mucus in the pathophysiology of death from asthma, but the role of mucus plugs in chronic severe asthma… read more here.
Keywords: airflow obstruction; mucus plugs; role mucus; mucus ... See more keywords