Modeled residual current cancer risk after clinical investigation of a positive multi-cancer early detection test result.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer"
DOI: 10.1002/cncr.34747
Abstract: Positive results of a multi‐cancer early detection (MCED) test require confirmatory diagnostic workup. Here, residual current cancer risk (RR) during the process of diagnostic resolution, including situations where the initial confirmatory test does not provide… read more here.
Keywords: residual current; test; cancer early; multi cancer ... See more keywords
Multi-cancer blood testing combined with PET-CT: road for hope to screen for cancer and guide intervention
Sign Up to like & getrecommendations! Published in 2020 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-020-0210-2
Abstract: In a recent study published in Science, Lennon et al. investigated the feasibility and safety of multi-cancer peripheral blood testing in combination with positron emission tomography-computed tomography (PET-CT) imaging to detect cancer in 10,006 women… read more here.
Keywords: test; soc screening; multi cancer; blood ... See more keywords
Novel germline variant in the histone demethylase and transcription regulator KDM4C induces a multi-cancer phenotype
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Medical Genetics"
DOI: 10.1136/jmedgenet-2021-107747
Abstract: Background Genes involved in epigenetic regulation are central for chromatin structure and gene expression. Specific mutations in these might promote carcinogenesis in several tissue types. Methods We used exome, whole-genome and Sanger sequencing to detect… read more here.
Keywords: histone demethylase; multi cancer; variant; cancer ... See more keywords
A Novel Blood-Based microRNA Diagnostic Model with High Accuracy for Multi-Cancer Early Detection
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14061450
Abstract: Simple Summary Development of noninvasive diagnostic tests capable of detecting multiple cancer types early is urgently needed. Majority of the tests that are currently in development for multi-cancer early detection are based on next generation… read more here.
Keywords: diagnostic model; multi cancer; model; cancer ... See more keywords