Biomimetic Liver Lobules from Multi‐Compartmental Microfluidics
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202406573
Abstract: Engineered liver lobule is highly practical in hepatic disease treatment, while constructing a 3D biomimetic lobule with a heterogeneous architecture on a large scale is challenging. Here, inspired by the natural architectural construction of hepatic… read more here.
Keywords: compartmental microfluidics; biomimetic liver; lobules multi; multi compartmental ... See more keywords
Within-Host Viral Dynamics in a Multi-compartmental Environment
Sign Up to like & getrecommendations! Published in 2019 at "Bulletin of Mathematical Biology"
DOI: 10.1007/s11538-019-00658-1
Abstract: The discrepancy in the turnover of cells and virus in different organs or viral reservoirs necessitates the investigation of multiple compartments within a host. Establishing a multi-compartmental structure that describes the complexity of various organs,… read more here.
Keywords: host viral; viral dynamics; multi compartmental; within host ... See more keywords
Multi-compartmental diversification of neutralizing antibody lineages dissected in SARS-CoV-2 spike-immunized macaques
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-50286-0
Abstract: The continued evolution of SARS-CoV-2 underscores the need to understand qualitative aspects of the humoral immune response elicited by spike immunization. Here, we combine monoclonal antibody (mAb) isolation with deep B cell receptor (BCR) repertoire… read more here.
Keywords: sars cov; antibody lineages; spike; antibody ... See more keywords
SECONIC: Towards multi-compartmental models for ultrasonic brain stimulation by intramembrane cavitation.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of neural engineering"
DOI: 10.1088/1741-2552/abb73d
Abstract: OBJECTIVE To design a computationally efficient model for ultrasonic neuromodulation (UNMOD) of morphologically realistic multi-compartmental neurons based on intramembrane cavitation. APPROACH A Spatially Extended Neuronal Intramembrane Cavitation model that accurately predicts observed fast Charge Oscillations… read more here.
Keywords: multi compartmental; model; neuronal intramembrane; intramembrane cavitation ... See more keywords
Multi-compartmental model of glymphatic clearance of solutes in brain tissue
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0280501
Abstract: The glymphatic system is the subject of numerous pieces of research in biology. Mathematical modelling plays a considerable role in this field since it can indicate the possible physical effects of this system and validate… read more here.
Keywords: clearance; system; brain; compartmental model ... See more keywords