Conditional probability and ratio‐based approaches for mapping the coverage of multi‐dose vaccines
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DOI: 10.1002/sim.9586
Abstract: Many vaccines are often administered in multiple doses to boost their effectiveness. In the case of childhood vaccines, the coverage maps of the doses and the differences between these often constitute an evidence base to… read more here.
Keywords: coverage multi; coverage; multi dose; dose vaccines ... See more keywords
Mechanism of Thimerosal-Induced Structural Destabilization of a Recombinant Rotavirus P[4] Protein Antigen Formulated as a Multi-Dose Vaccine
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DOI: 10.1016/j.xphs.2020.11.033
Abstract: In a companion paper, a two-step developability assessment is presented to rapidly evaluate low-cost formulations (multi-dose, aluminum-adjuvanted) for new subunit vaccine candidates. As a case study, a non-replicating rotavirus (NRRV) recombinant protein antigen P[4] was… read more here.
Keywords: protein; thimerosal; mechanism; antigen ... See more keywords
Maximizing number of doses drawn from multi-dose COVID-19 vaccines by minimizing dead-volume
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DOI: 10.1093/jtm/taab049
Abstract: Maximizing number of doses drawn from multi-dose COVID-19 vaccines by minimizing dead-volume Brendan Le Daré, PharmD, PhD1,2,*, Astrid Bacle, PharmD, PhD1,3, Roxane Lhermitte1, François Lesourd, PharmD1, and Yves Lurton, PharmD1 1Centre Hospitalier Universitaire de Rennes,… read more here.
Keywords: number doses; maximizing number; doses drawn; dose covid ... See more keywords
Pharmacokinetics of dipyrone in horses: A multi-dose, dose escalation study.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of veterinary pharmacology and therapeutics"
DOI: 10.1111/jvp.12996
Abstract: Dipyrone is a non-opioid, nonsteroidal anti-inflammatory drug with antipyretic and analgesic properties commonly used in horses. Dipyrone is rapidly hydrolyzed to the primary active metabolite 4-methylaminoantipyrine (4-MAA). The purpose of this study was to determine… read more here.
Keywords: dipyrone horses; pharmacokinetics dipyrone; study; dipyrone ... See more keywords
Pharmacokinetics of paracetamol in the Thoroughbred horse following an oral multi-dose administration.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of veterinary pharmacology and therapeutics"
DOI: 10.1111/jvp.13024
Abstract: Paracetamol is a widely used, non-opioid analgesic and antipyretic drug. Scientific evidence suggests that it is an effective pain treatment in equine medicine. However, there is very little published information about the pharmacokinetics of the… read more here.
Keywords: pharmacokinetics paracetamol; administration; paracetamol thoroughbred; multi dose ... See more keywords
Vilazodone Hydrochloride Multi-Dose Nasal Spray Solution for the Treatment of Depression: Design, Optimization, and Evaluation
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DOI: 10.2174/1574885516666210405110302
Abstract: The aim of present research work was to prepare, optimized, and evaluate the multi-dose nasal spray solution for delivery of vilazodone hydrochloride to the brain by the intranasal route in order to overcome the drawback… read more here.
Keywords: dose nasal; spray solution; vilazodone hydrochloride; solution ... See more keywords