The Occurrence of Type I, II, and III Integrons in Multi-drug Resistance and Methicillin-Resistant Staphylococcus aureus Isolates in Iran
Sign Up to like & getrecommendations! Published in 2020 at "Current Microbiology"
DOI: 10.1007/s00284-020-01956-x
Abstract: Integrons are mobilizable platforms-DNA elements with impacts on moving antibiotic resistance genes among bacteria and capable of spreading multi-drug resistance (MDR) in pathogens. Methicillin-resistant Staphylococcus aureus (MRSA) strains are the main cause of community-acquired and… read more here.
Keywords: aureus; iii integrons; resistance; multi drug ... See more keywords
Role of environmental surfaces and hands of healthcare workers in perpetuating multi-drug-resistant pathogens in a neonatal intensive care unit
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DOI: 10.1007/s00431-021-04241-6
Abstract: Neonates admitted to neonatal intensive care units are at a risk of developing healthcare-associated infections, leading to increased risk of mortality. This study aimed to identify organisms causing such late-onset infections in neonates and determine… read more here.
Keywords: intensive care; drug resistant; multi drug; healthcare workers ... See more keywords
A Three-drug co-Delivery System Based on Reduction-sensitive Pol-ymeric Prodrug to Effectively Reverse Multi-drug Resistance
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Research in Chinese Universities"
DOI: 10.1007/s40242-017-6450-1
Abstract: In the present study, we prepared a multi-drug delivery system based on reduction-sensitive paclitaxel (PTX) polymeric prodrug(PEG-b-PMPMC-g-PTX, PMP) polymersomes to co-deliver PTX, doxorubicin hydrochloride(DOX·HCl) and the P-glycoprotein(P-gp) inhibitor Tariquidar(TQR) to effectively reverse drug resistance by… read more here.
Keywords: drug; dox hcl; multi drug; reduction sensitive ... See more keywords
Extraction and partial purification of secondary metabolites from endophytic actinomycetes of marine green algae Caulerpa racemosa against multi drug resistant uropathogens
Sign Up to like & getrecommendations! Published in 2019 at "Biocatalysis and Agricultural Biotechnology"
DOI: 10.1016/j.bcab.2019.01.016
Abstract: Abstract The aim of this study is to identify potential antibacterial compounds of endophytic actinomycetes (EA) from marine algae Caulerpa racemosa for inhibit the multi drug resistant (MDR) Gram negative bacteria (GNB) including Eschericia coli… read more here.
Keywords: drug resistant; caulerpa racemosa; multi drug; actinomycetes marine ... See more keywords
Total synthesis of acylphloroglucinols and their antibacterial activities against clinical isolates of multi-drug resistant (MDR) and methicillin-resistant strains of Staphylococcus aureus.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.05.038
Abstract: Bioassay-directed drug discovery efforts focusing on various species of the genus Hypericum led to the discovery of a number of new acylphloroglucinols including (S,E)-1-(2-((3,7-dimethylocta-2,6-dien-1-yl)oxy)-4,6-dihydroxyphenyl)-2-methylbutan-1-one (6, olympicin A) from H. olympicum, with MICs ranging from 0.5… read more here.
Keywords: isolates multi; chemistry; drug; multi drug ... See more keywords
Evaluation of N-phenyl-2-aminothiazoles for treatment of multi-drug resistant and intracellular Staphylococcus aureus infections.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2020.112497
Abstract: The increasing emergence of antibiotic-resistant bacterial pathogens calls for additional urgency in the development of new antibacterial candidates. N-Phenyl-2-aminothiazoles are promising candidates that possess potent anti-MRSA activity and could potentially replenish the MRSA antibiotic pipeline.… read more here.
Keywords: treatment multi; evaluation phenyl; drug resistant; aminothiazoles treatment ... See more keywords
A new multifunctionalized material against multi‐drug resistant bacteria and abnormal osteoclast activity
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2018.02.018
Abstract: Graphical abstract Figure. No caption available. &NA; The development of new biomaterials able to favor bone formation and to inhibit bone abnormal resorption is mandatory to face the increasing number of age‐related musculo‐skeletal disorders. Moreover,… read more here.
Keywords: activity; drug resistant; multi drug; new multifunctionalized ... See more keywords
Glutathione and the switch of aerobic metabolism collaborate for multi-drug resistance of neuroblastoma
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.04.236
Abstract: The availability of antioxidants is recognized as one of the critical factors able to make cancer cells resistant to chemotherapy. In this context, it has been demonstrated that many chemoresistant cancers display high levels of… read more here.
Keywords: drug resistance; metabolism collaborate; metabolism; switch aerobic ... See more keywords
Accelerating development of new shorter TB treatment regimens in anticipation of a resurgence of multi-drug resistant TB due to the COVID-19 pandemic
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Infectious Diseases"
DOI: 10.1016/j.ijid.2021.02.067
Abstract: The WHO 2020 global TB Report estimates that in 2019 there were an estimated 500,000 cases of multi-drug resistant TB (MDR-TB) of which only 186,772 MDR-TB cases were diagnosed, and positive treatment outcomes were achieved… read more here.
Keywords: mdr; treatment; drug; covid ... See more keywords
A patient with central nervous system tuberculomas and a history of disseminated multi-drug-resistant tuberculosis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Tuberculosis and Other Mycobacterial Diseases"
DOI: 10.1016/j.jctube.2017.12.004
Abstract: Tuberculosis (TB) is one of the leading causes of death worldwide, particularly in low- and middle-income countries. The global rates and numbers of drug resistant TB are rising. With increasing globalization, the spread of drug-resistant… read more here.
Keywords: nervous system; central nervous; drug; drug resistant ... See more keywords
Multi-drug resistant tuberculosis, ten years later
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DOI: 10.1016/j.medcle.2020.08.009
Abstract: Drug-resistant tuberculosis, especially those with resistance to rifampicin (RR-TB), has become one of the main obstacles to achieving the dream of eradicating tuberculosis. Furthermore, it is necessary to combine three or four different drugs in… read more here.
Keywords: resistant tuberculosis; tuberculosis ten; drug resistant; tuberculosis ... See more keywords