Articles with "multi organ" as a keyword



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Multi‐organ carcinogenicity by inhalation exposure to 2‐Bromopropane in rats

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Published in 2023 at "Journal of Occupational Health"

DOI: 10.1002/1348-9585.12388

Abstract: Abstract Objective The purpose of this study was to investigate the carcinogenicity of 2‐bromopropane (2‐BP) in rats. Methods Male and female F344 rats were exposed by whole body inhalation to 2‐BP vapor at concentrations of… read more here.

Keywords: carcinogenicity; multi organ; gland; inhalation exposure ... See more keywords
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A pumpless multi‐organ‐on‐a‐chip (MOC) combined with a pharmacokinetic–pharmacodynamic (PK–PD) model

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Published in 2017 at "Biotechnology and Bioengineering"

DOI: 10.1002/bit.26087

Abstract: A multi‐organ‐on‐a‐chip (MOC), also known as a human‐on‐a‐chip, aims to simulate whole body response to drugs by connecting microscale cell cultures of multiple tissue types via fluidic channels and reproducing the interaction between them. While… read more here.

Keywords: organ chip; chip moc; model; multi organ ... See more keywords
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Common laboratory parameters as indicators of multi‐organ dysfunction in acute heart failure

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Published in 2019 at "European Journal of Heart Failure"

DOI: 10.1002/ejhf.1466

Abstract: Understanding of diagnosis, classification, pathophysiology, prognosis, and treatment of heart failure remains of major interest in clinical cardiology.1 There are approximately 23 million people with heart failure worldwide,2 and that estimate is expected to increase… read more here.

Keywords: dysfunction; heart failure; acute heart; multi organ ... See more keywords
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Potential of circulating lncRNA CASC2 as a biomarker in reflecting the inflammatory cytokines, multi‐organ dysfunction, disease severity, and mortality in sepsis patients

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Published in 2022 at "Journal of Clinical Laboratory Analysis"

DOI: 10.1002/jcla.24569

Abstract: Long noncoding RNA (lncRNA) cancer susceptibility candidate gene 2 (CASC2) inhibits inflammation and multi‐organ dysfunction in various ways. The present study was intended to explore the potency of blood lncRNA CASC2 as a biomarker for… read more here.

Keywords: casc2 biomarker; casc2; organ dysfunction; multi organ ... See more keywords
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Variance-aware attention U-Net for multi-organ segmentation.

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Published in 2021 at "Medical physics"

DOI: 10.1002/mp.15322

Abstract: PURPOSE With the continuous development of deep learning based medical image segmentation technology, it is expected to attain more robust and accurate performance for more challenging tasks, such as multi-organs, small/irregular areas, and ambiguous boundary issues.… read more here.

Keywords: segmentation; attention; variance; multi organ ... See more keywords
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Nested-block self-attention multiple resolution residual network for multi-organ segmentation from CT.

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Published in 2022 at "Medical physics"

DOI: 10.1002/mp.15765

Abstract: BACKGROUND Fast and accurate multi-organs segmentation from CT scans is essential for radiation treatment planning. Self-attention based deep learning methodologies provide higher accuracies than standard methods but require memory and computationally intensive calculations, which restricts… read more here.

Keywords: self attention; multi organ; attention; nested block ... See more keywords
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Salient deformable network for abdominal multi-organ registration.

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Published in 2022 at "Medical physics"

DOI: 10.1002/mp.15791

Abstract: BACKGROUND Image registration has long been an active research area in the society of medical image computing, which is to perform spatial transformation between a pair of images and establish a point-wise correspondence to achieve… read more here.

Keywords: network; deformable network; registration; multi organ ... See more keywords
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Neuropeptide W Attenuates Oxidative Multi-Organ Injury in Rats Induced with Intra-Abdominal Sepsis.

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Published in 2021 at "Inflammation"

DOI: 10.1007/s10753-021-01545-5

Abstract: Sepsis leads to systemic hypotension, disturbed perfusion, inflammation, and tissue toxicity in vital organs. Neuropeptide W (NPW) has modulatory effects in the control of blood pressure and inflammatory processes, implicating a potential beneficial effect against… read more here.

Keywords: sepsis; attenuates oxidative; neuropeptide attenuates; oxidative multi ... See more keywords
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DenseRes-Unet: Segmentation of overlapped/clustered nuclei from multi organ histopathology images

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Published in 2022 at "Computers in biology and medicine"

DOI: 10.1016/j.compbiomed.2022.105267

Abstract: Cancer is the second deadliest disease globally that can affect any human body organ. Early detection of cancer can increase the chances of survival in humans. Morphometric appearances of histopathology images make it difficult to… read more here.

Keywords: histopathology; segmentation; model; multi organ ... See more keywords
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The value of tumour debulking for patients with extensive multi-organ metastatic colorectal cancer.

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Published in 2018 at "European journal of cancer"

DOI: 10.1016/j.ejca.2018.07.012

Abstract: Local treatment of metastases by surgical resection or other ablative therapies is technically feasible in an increasing number of patients with multi-organ metastatic cancer. This results in a growing debate on whether patients with extensive… read more here.

Keywords: colorectal cancer; local treatment; multi organ; cancer ... See more keywords
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Recurrent necrotizing cellulitis, multi-organ autoimmune disease and humoral immunodeficiency due to a novel NFKB1 frameshift mutation.

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Published in 2021 at "European journal of medical genetics"

DOI: 10.1016/j.ejmg.2021.104144

Abstract: BACKGROUND Mutations in NFKB1(nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) are associated with a variety of clinical symptoms, including lymphadenopathy, splenomegaly, hepatomegaly, autoimmune haemolytic anaemia, arthralgia, recurrent respiratory tract infections and… read more here.

Keywords: necrotizing cellulitis; frameshift mutation; cellulitis; multi organ ... See more keywords