Combined multi-pharmacophore, molecular docking and molecular dynamic study for discovery of promising MTH1 inhibitors
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DOI: 10.1016/j.molstruc.2017.02.034
Abstract: Abstract MutT homolog 1 (MTH1), a nudix phosphohydrolase enzyme participates in the process of repairing of DNA damage by hydrolyzing oxidized deoxy-ribonucleoside triphosphate in cancer cells, is regarded as a potential target for anticancer therapy.… read more here.
Keywords: promising mth1; pharmacophore molecular; multi pharmacophore; combined multi ... See more keywords