Articles with "multi protein" as a keyword



In Vitro Formation of a Multi-Protein Complex Involved in TCR Signaling

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Published in 2017 at "Biophysical Journal"

DOI: 10.1016/j.bpj.2016.11.2878

Abstract: The T cell antigen receptor (TCR) binds a ligand consisting of antigenic peptide bound to a cell surface molecule encoded by the major histocompatibility complex (pMHC) to begin the process of T cell activation. TCR… read more here.

Keywords: protein; tcr; vitro formation; multi protein ... See more keywords

Dissecting the signaling features of the multi-protein complex GPCR/β-arrestin/ERK1/2.

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Published in 2018 at "European journal of cell biology"

DOI: 10.1016/j.ejcb.2018.04.001

Abstract: G protein-coupled receptors (GPCRs) have emerged as key biological entities that regulate a plethora of physiological processes and participate in the onset and development of many diseases. Moreover, these receptors are important targets of almost… read more here.

Keywords: protein; protein complex; complex gpcr; features multi ... See more keywords

Studies of recombinant TWA1 reveal constitutive dimerization

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Published in 2017 at "Bioscience Reports"

DOI: 10.1042/bsr20160401

Abstract: The mammalian muskelin/RanBP9/C-terminal to LisH (CTLH) complex and the Saccharomyces cerevisiae glucose-induced degradation (GID) complex are large, multi-protein complexes that each contain a RING E3 ubiquitin ligase. The yeast GID complex acts to degrade a… read more here.

Keywords: protein; gid complex; multi protein; lish ctlh ... See more keywords

A pan-respiratory antiviral chemotype targeting a transient host multi-protein complex

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Published in 2024 at "Open Biology"

DOI: 10.1098/rsob.230363

Abstract: We present a novel small molecule antiviral chemotype that was identified by an unconventional cell-free protein synthesis and assembly-based phenotypic screen for modulation of viral capsid assembly. Activity of PAV-431, a representative compound from the… read more here.

Keywords: host; multi protein; protein; respiratory ... See more keywords