Nitroxoline: an option for the treatment of urinary tract infection with multi-resistant uropathogenic bacteria
Sign Up to like & getrecommendations! Published in 2018 at "Infection"
DOI: 10.1007/s15010-018-1253-y
Abstract: The number of multi-resistant uropathogens is increasing. A multi-morbid patient developed a symptomatic urinary tract infection with two multi-resistant bacteria, namely Klebsiella pneumoniae and Proteus mirabilis. Nitroxoline was the only drug active against both uropathogens.… read more here.
Keywords: urinary tract; tract infection; infection; multi resistant ... See more keywords
ZnAl layered double hydroxides impregnated with eucalyptus oil as efficient hybrid materials against multi-resistant bacteria
Sign Up to like & getrecommendations! Published in 2018 at "Applied Clay Science"
DOI: 10.1016/j.clay.2017.11.017
Abstract: Abstract Bacterial contamination poses a serious hazard for human health. The use of bactericidal materials, such as layered double hydroxides, might constitute a way to reduce the risk of diseases. In this work, ZnAl layered… read more here.
Keywords: layered double; eucalyptus oil; multi resistant; double hydroxides ... See more keywords
Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c00734
Abstract: We report a series of synthetic cationic amphipathic barbiturates inspired by the pharmacophore model of small antimicrobial peptides (AMPs) and the marine antimicrobials eusynstyelamides. These N,N'-dialkylated-5,5-disubstituted barbiturates consist of an achiral barbiturate scaffold with two… read more here.
Keywords: amphipathic barbiturates; barbiturates mimics; resistant clinical; multi resistant ... See more keywords
TKI rotation-induced persistent deep molecular response in multi-resistant blast crisis of Ph+ CML
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.15481
Abstract: In chronic myeloid leukemia (CML) resistance against one or more BCR-ABL1 tyrosine kinase inhibitors (TKI) remains a clinical challenge. Preclinical data suggest that TKI combinations may overcome resistance. We report on a heavily pre-treated 78… read more here.
Keywords: blast; cml; rotation; multi resistant ... See more keywords
Combination of Six Individual Derivatives of the Pom-1 Antibiofilm Peptide Doubles Their Efficacy against Invasive and Multi-Resistant Clinical Isolates of the Pathogenic Yeast Candida albicans
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14071332
Abstract: In previous studies, derivatives of the peptide Pom-1, which was originally extracted from the freshwater mollusk Pomacea poeyana, showed an exceptional ability to specifically inhibit biofilm formation of the laboratory strain ATCC 90028 as a… read more here.
Keywords: derivatives pom; yeast candida; pathogenic yeast; multi resistant ... See more keywords
Epidemiological, Microbiological, and Clinical Characteristics of Multi-Resistant Pseudomonas aeruginosa Isolates in King Fahad Medical City, Riyadh, Saudi Arabia
Sign Up to like & getrecommendations! Published in 2023 at "Tropical Medicine and Infectious Disease"
DOI: 10.3390/tropicalmed8040205
Abstract: Increasing rates of serious multi-drug resistant (MDR) Pseudomonas aeruginosa infections have been reported globally, including in Saudi Arabia. This retrospective study investigates the epidemiological, microbiological, and clinical characteristics of multi-resistant P. aeruginosa (n3579 clinical isolates)… read more here.
Keywords: microbiological clinical; saudi arabia; pseudomonas aeruginosa; epidemiological microbiological ... See more keywords