Multicatalysis protocol enables direct and versatile enantioselective reductive transformations of secondary amides
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DOI: 10.1126/sciadv.ade3431
Abstract: The catalytic asymmetric geminal bis-nucleophilic addition to nonreactive functional groups is a type of highly desirable yet challenging transformation in organic chemistry. Here, we report the first catalytic asymmetric reductive/deoxygenative alkynylation of secondary amides. The… read more here.
Keywords: secondary amides; multicatalysis protocol; enantioselective reductive; protocol ... See more keywords