Mathematical and In Silico Analysis of Synthetic Inhibitory Circuits That Program Self-Organizing Multicellular Structures.
Sign Up to like & getrecommendations! Published in 2024 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.4c00230
Abstract: Bottom-up approaches are becoming increasingly popular for studying multicellular self-organization and development. In contrast to the classic top-down approach, where parts of the organization/developmental process are broken to understand the process, the goal is to… read more here.
Keywords: inhibitory circuits; multicellular structures; synthetic inhibitory; self ... See more keywords
Self-organizing multicellular structures designed using synthetic biology
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DOI: 10.1038/d41586-018-05564-5
Abstract: Synthetic genetic circuits can induce cells to form simple 3D structures reminiscent of those generated during early embryonic development. This advance will help engineers build tissues that have desirable structures.Synthetic genetic circuits can induce cells… read more here.
Keywords: multicellular structures; organizing multicellular; designed using; structures designed ... See more keywords
The Capacity of High-Grade Serous Ovarian Cancer Cells to Form Multicellular Structures Spontaneously along Disease Progression Correlates with Their Orthotopic Tumorigenicity in Immunosuppressed Mice
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DOI: 10.3390/cancers12030699
Abstract: Many studies have examined the biology, genetics, and chemotherapeutic response of ovarian cancer’s solid component; its liquid facet, however, remains critically underinvestigated. Floating within peritoneal effusions known as ascites, ovarian cancer cells form multicellular structures,… read more here.
Keywords: multicellular structures; serous ovarian; capacity; ovarian cancer ... See more keywords