Synthetic developmental biology: build and control multicellular systems.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2019.04.006
Abstract: Synthetic biology offers a bottom-up engineering approach that intends to understand complex systems via design-build-test cycles. Embryonic development comprises complex processes that originate at the level of gene regulatory networks in a cell and emerge… read more here.
Keywords: control; developmental biology; biology build; synthetic developmental ... See more keywords
Engineering multicellular systems: using synthetic biology to control tissue self-organization.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in biomedical engineering"
DOI: 10.1016/j.cobme.2017.10.008
Abstract: Abstract The control of multicellular systems in general and of tissue formation in particular is a frontier for regenerative medicine and basic biological research. Current manipulations of multicellular systems such as tissue engineering, in vitro organoid… read more here.
Keywords: engineering; control; tissue; biology ... See more keywords
3D multicellular systems in disease modelling: From organoids to organ-on-chip
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1083175
Abstract: Cell-cell interactions underlay organ formation and function during homeostasis. Changes in communication between cells and their surrounding microenvironment are a feature of numerous human diseases, including metabolic disease and neurological disorders. In the past decade,… read more here.
Keywords: cell; systems disease; multicellular systems; organ chip ... See more keywords