A multicentre, open-label, single-arm phase II trial of the efficacy and safety of sclerotherapy using 3% polidocanol foam to treat second-degree haemorrhoids (SCLEROFOAM)
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DOI: 10.1007/s10151-022-02609-w
Abstract: The aim of the present study was to evaluate the efficacy and safety of 3% polidocanol foam for treating 2nd-degree haemorrhoids. A multicentre, open-label, single-arm, phase 2 trial involving 10 tertiary referral centres for haemorrhodal… read more here.
Keywords: efficacy safety; open label; polidocanol foam; degree haemorrhoids ... See more keywords
A multicentre, open-label, phase-I/randomised phase-II study to evaluate safety, pharmacokinetics, and efficacy of nintedanib vs. sorafenib in European patients with advanced hepatocellular carcinoma
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DOI: 10.1038/s41416-018-0051-8
Abstract: BackgroundThis multicentre, open-label, phase-I/randomised phase-II trial evaluated safety, pharmacokinetics, maximum-tolerated-dose (MTD) per dose-limiting toxicities (DLTs), and efficacy of nintedanib vs. sorafenib in European patients with unresectable advanced hepatocellular carcinoma (aHCC).MethodsPhase I: Patients were stratified into… read more here.
Keywords: open label; phase; phase randomised; label phase ... See more keywords