Serplulimab combined with gemcitabine, nab-paclitaxel and stereotactic body radiotherapy as the first-line treatment for patients with metastatic pancreatic adenocarcinoma in China: a multicentre, single-arm, phase II trial (ICSBR) protocol
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DOI: 10.1136/bmjopen-2024-084274
Abstract: Introduction Patients with pancreatic ductal adenocarcinoma (PDAC) remain a poor prognosis despite the development of chemotherapy. Although programmed cell death 1 (PD-1) blockade has shown great efficacy in various solid tumours, its application in treating… read more here.
Keywords: stereotactic body; multicentre single; trial; patients metastatic ... See more keywords
Efficacy and safety of radiotherapy to delay second-line systemic therapy in patients with oligoprogressive hepatocellular carcinoma: study protocol of a multicentre, single-arm, phase II trial
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DOI: 10.1177/17588359251334538
Abstract: Background: Hepatocellular carcinoma (HCC) is a highly aggressive cancer with a paucity of efficacious treatment options, particularly in advanced stages following first-line systemic therapy (FLST). Objectives: The objective of this trial is to assess the… read more here.
Keywords: single arm; multicentre single; trial; patients oligoprogressive ... See more keywords