Treatment of Kaposi Sarcoma Herpesvirus-Associated Multicentric Castleman Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Hematology/oncology clinics of North America"
DOI: 10.1016/j.hoc.2017.09.007
Abstract: Kaposi sarcoma herpesvirus (KSHV)-associated multicentric Castleman disease (MCD) is a rare, polyclonal lymphoproliferative disorder characterized by flares of inflammatory symptoms, edema, cytopenias, lymphadenopathy, and splenomegaly. Diagnosis requires a lymph node biopsy. Pathogenesis is related to… read more here.
Keywords: kaposi sarcoma; treatment; associated multicentric; castleman disease ... See more keywords
Concurrent HIV viral blips during two episodes of multicentric Castleman disease in an adult on antiretroviral therapy: Implication for HIV persistence
Sign Up to like & getrecommendations! Published in 2021 at "IDCases"
DOI: 10.1016/j.idcr.2021.e01315
Abstract: Human herpesvirus-8 (HHV8)-associated multicentric Castleman disease (HHV8-MCD) is a rare nonmalignant lymphoproliferative disorder most commonly observed in PLWH. Herein, we describe an HIV-infected adult male from Cameroon with relapsing HHV8-MCD (HIV+MCD). The patient developed constitutional… read more here.
Keywords: therapy; hiv; multicentric castleman; disease ... See more keywords
A case of acute progressive diffuse interstitial lung disease preceding idiopathic multicentric Castleman disease
Sign Up to like & getrecommendations! Published in 2020 at "Respiratory Medicine Case Reports"
DOI: 10.1016/j.rmcr.2020.101216
Abstract: It has been considered that idiopathic multicentric Castleman disease often involves pulmonary complications recognized as lymphocytic interstitial pneumonia. On the other hand, recent reports show that the computed tomography often show diffuse interstitial lung disease… read more here.
Keywords: disease; castleman disease; multicentric castleman; idiopathic multicentric ... See more keywords
A case of TAFRO syndrome, a variant of multicentric Castleman’s disease, successfully treated with corticosteroid and cyclosporine A
Sign Up to like & getrecommendations! Published in 2019 at "Modern Rheumatology"
DOI: 10.1080/14397595.2016.1206243
Abstract: Abstract We report a case of a 46-year-old woman with fever, pleural effusion, massive ascites, severe edema, hepatosplenomegaly, elevation of serum creatinine level, proteinuria, and severe thrombocytopenia. Her clinical features were compatible with TAFRO syndrome… read more here.
Keywords: case; castleman disease; variant multicentric; multicentric castleman ... See more keywords
An open-label continuation trial of sirolimus for tocilizumab-refractory idiopathic multicentric Castleman disease
Sign Up to like & getrecommendations! Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000023291
Abstract: Abstract Background: Interleukin 6 (IL-6) inhibitors are the first-line treatment for idiopathic multicentric Castleman disease (iMCD); however, there is no established treatment for cases that are resistant to IL-6 inhibitors. Although sirolimus, a mammalian target… read more here.
Keywords: castleman disease; idiopathic multicentric; multicentric castleman; open label ... See more keywords
Human herpesvirus 8-associated multicentric Castleman disease in a patient with advanced HIV infection
Sign Up to like & getrecommendations! Published in 2021 at "Medicine"
DOI: 10.1097/md.0000000000028077
Abstract: Abstract Rational: Multicentric Castleman disease (MCD) is a nonclonal lymphoproliferative disorder that is rarely reported from Southeast Asian countries. Here, we report a case of human herpesvirus 8 (HHV-8)-associated MCD in a patient with advanced… read more here.
Keywords: patient; hiv infection; advanced hiv; disease ... See more keywords
Multicentric Castleman’s disease of the lungs mimicking a multifocal adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2022-250249
Abstract: A female patient presented with fever of unknown origin, night sweats and weight loss. She had no pulmonary symptoms. Investigations revealed bilateral ground glass lung lesions which were subsequently followed-up with imaging. Two years later,… read more here.
Keywords: lung; multicentric castleman; castleman disease; disease lungs ... See more keywords
Case of idiopathic multicentric Castleman’s disease: the master mimicker
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2022-250706
Abstract: A woman in her 20s with no medical history presented with progressive abdominal distension, right-sided abdominal discomfort, fatigue and nausea. Examination showed multifocal lymphadenopathy and hepatomegaly with tense ascites. Investigations revealed a multisystem inflammatory condition… read more here.
Keywords: multicentric castleman; disease; castleman disease; case idiopathic ... See more keywords
Diffuse cryptococcal pneumonia in multicentric Castleman’s disease with elevated serum IgG4
Sign Up to like & getrecommendations! Published in 2023 at "BMJ Case Reports"
DOI: 10.1136/bcr-2022-252595
Abstract: A woman in her 60s with suspected multicentric Castleman’s disease, who was receiving treatment with oral prednisolone, presented to our hospital with mild cough and malaise. Chest CT showed diffuse infiltrative and granular shadows, indicating… read more here.
Keywords: castleman; castleman disease; multicentric castleman; diffuse cryptococcal ... See more keywords
Multicentric Castleman disease and concurrent hematological disorders: the occurrence of plasmacytoma and the hypotheses arising from literature's review.
Sign Up to like & getrecommendations! Published in 2023 at "Acta haematologica"
DOI: 10.1159/000530601
Abstract: The concomitant presence of Castleman disease with other hematological pathology is an event described in the literature with increasing frequency, able to modify the diagnostic and curative approach in such patients. Very few studies in… read more here.
Keywords: disease concurrent; plasmacytoma; castleman disease; multicentric castleman ... See more keywords
iNKT and memory B-cell alterations in HHV-8 multicentric Castleman disease.
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood-2016-06-719716
Abstract: Human herpesvirus 8 (HHV-8) is the causative agent of Kaposi sarcoma (KS) and multicentric Castleman disease (MCD), a life-threatening, virally induced B-cell lymphoproliferative disorder. HHV-8 is a B-lymphotropic γ-herpesvirus closely related to the Epstein-Barr virus… read more here.
Keywords: castleman disease; cell alterations; multicentric castleman; cell ... See more keywords