Multicomponent Approach to Libraries of Substituted Dihydroorotic Acid Amides.
Sign Up to like & getrecommendations! Published in 2019 at "ACS combinatorial science"
DOI: 10.1021/acscombsci.9b00144
Abstract: A process featuring a sequential multicomponent reaction followed by regioselective post-cyclization strategy was implemented for the facile synthesis of N,N'-disubstituted dihydroorotic acid amides in very mild condition. We obtained, for the first time, a library… read more here.
Keywords: approach libraries; acid amides; multicomponent approach; dihydroorotic acid ... See more keywords
Effective Synthesis and Biological Evaluation of Functionalized 2,3-Dihydrofuro[3,2-c]coumarins via an Imidazole-Catalyzed Green Multicomponent Approach
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c05361
Abstract: For the first time, an eco-friendly and efficient one-pot green multicomponent approach has been described to synthesize functionalized trans-2,3-dihydrofuro[3,2-c]coumarins (DHFCs). In this synthesis, imidazole and water were used as the catalyst and solvent, respectively, under… read more here.
Keywords: synthesis; green multicomponent; multicomponent approach; dihydrofuro coumarins ... See more keywords