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   Articles with "multicomponent cascade" as a keyword



Iodine-Mediated Multicomponent Cascade Cyclization and Sulfenylation/Selenation: Synthesis of Imidazo[2,1-a]isoquinoline Derivatives.

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recommendations! Published in 2022 at "Organic letters"

DOI: 10.1021/acs.orglett.2c01681

Abstract: A novel multicomponent cascade cyclization and sulfenylation/selenation using aryl methyl ketones, isoquinolin-1-amine, and sodium arylsulfinates/1,2-diphenyldiselane to synthesize imidazo[2,1-a]isoquinoline derivatives in one-pot via the construction of two C-N bonds and one C-S/C-Se bond has been reported.… read more here.

Keywords: sulfenylation; cyclization sulfenylation; cascade cyclization; multicomponent cascade ... See more keywords

Assembly of Nitrated Isoxazoles via a Multicomponent Cascade Reaction Using Benzoxathiazine-2,2-dioxides as C1 Synthons.

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recommendations! Published in 2025 at "Organic letters"

DOI: 10.1021/acs.orglett.5c04070

Abstract: A novel multicomponent cascade reaction involving benzoxathiazine-2,2-dioxides, styrenes, and sodium nitrite has been developed. This method provides a facile and practical one-pot route to nitrated isoxazoles under transition-metal-free conditions. Notably, it first utilizes benzoxathiazine-2,2-dioxides as… read more here.

Keywords: dioxides synthons; multicomponent cascade; nitrated isoxazoles; cascade reaction ... See more keywords

Organocatalytic Asymmetric Multicomponent Cascade Reaction for the Synthesis of Contiguously Substituted Tetrahydronaphthols.

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recommendations! Published in 2021 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.1c03923

Abstract: Isobenzopyrylium ions are unique, highly reactive, aromatic intermediates which are largely unexplored in asymmetric catalysis despite their high potential synthetic utility. In this study, an organocatalytic asymmetric multicomponent cascade via dienamine catalysis, involving a cycloaddition,… read more here.

Keywords: multicomponent cascade; asymmetric multicomponent; organocatalytic asymmetric; reaction ... See more keywords