Improving mechanical properties of desloratadine via multicomponent crystal formation
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2017.09.035
Abstract: ABSTRACT We report the first multicomponent crystal of desloratadine, an important anti‐histamine drug, with a pharmaceutically acceptable coformer of benzoic acid. The single crystal structure analysis revealed that this novel multicomponent crystal is categorized as… read more here.
Keywords: improving mechanical; benzoic acid; multicomponent crystal; mechanical properties ... See more keywords
A Drug–Drug Multicomponent Crystal of Metformin and Dobesilate: Crystal Structure Analysis and Hygroscopicity Property
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DOI: 10.3390/molecules27113472
Abstract: A drug–drug multicomponent crystal consisting of metformin (MET) and dobesilate (DBS) was prospectively connected by solvent cooling and evaporating co-crystallization using the multicomponent crystal strategy, not only to optimize the physicochemical properties of single drugs,… read more here.
Keywords: crystal; structure; drug drug; drug multicomponent ... See more keywords