MULTICOMPONENT SYNTHESIS OF UNSYMMETRICAL 5-NITROPYRIDINES
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/4746
Abstract: Reaction of 2-nitroacetophenone, furfurol, β-dicarbonyl compounds, and ammonium acetate led to 3-substituted 4-(2-furyl)-5-nitro-6-phenyl-1,4-dihydropyridines, which were oxidized with potassium nitrate in the presence of copper(II) nitrate (10 mol %), leading to the respective 5-nitro-6-phenylpyridines. The performed… read more here.
Keywords: multicomponent synthesis; chemistry; unsymmetrical nitropyridines; synthesis unsymmetrical ... See more keywords
MULTICOMPONENT SYNTHESIS AND MOLECULAR STRUCTURE OF 3-AMINO-2-AROYL(ALKOXYCARBONYL, ARYLCARBAMOYL)-4-ARYL(HETARYL)- 5-ARYLCARBAMOYL-6-METHYLTHIENO[2,3- b ]PYRIDINES
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/4976
Abstract: Разработан новый эффективный метод синтеза функционализированных тиено[2,3- b ]пиридинов многокомпонентной конденсацией ароматических и гетероароматических альдегидов, цианотиоацетамида, ацетоацетанилидов и метиленактивных алкилирующих реагентов. Строение 3-амино-2-бензоил-6-метил- N -фенил-4-(фуран-2-ил)тиено[2,3- b ]пиридин-5-карбоксамида, 3-амино- N 2 -(4-бромфенил)-6-метил-4-(3-метилтиофен-2-ил)- N 5 -(4-хлорфенил)тиено[2,3- b… read more here.
Keywords: amino aroyl; molecular structure; multicomponent synthesis; structure amino ... See more keywords
Efficient multicomponent synthesis of propargylamines catalyzed by copper nanoparticles supported on metal-organic framework derived nanoporous carbon
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DOI: 10.1016/j.catcom.2016.10.030
Abstract: Abstract Cu nanoparticles were deposited on nanoporous carbon, MOF-5-C, which was fabricated by direct carbonization of MOF-5 without any additional carbon sources. The as-obtained catalyst (Cu@MOF-5-C) exhibited high catalytic activity due to the high surface… read more here.
Keywords: efficient multicomponent; carbon; synthesis propargylamines; multicomponent synthesis ... See more keywords
Activity of immobilized metallic phthalocyanines in the multicomponent synthesis of dihydropyridine derivatives and their subsequent aromatization
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Catalysis"
DOI: 10.1016/j.mcat.2017.03.010
Abstract: Abstract Several supported metallo-sulphonated phthalocyanines (FePcS-NH 2 -SiO 2 , CoPcS-NH 2 -SiO 2 , and CuPcS-NH 2 -SiO 2 ) and iron hexadecachlorinated phthalocyanines (FePcCl 16 -NH 2 -SiO 2 and FePcCl 16 -NH… read more here.
Keywords: metallic phthalocyanines; multicomponent synthesis; immobilized metallic; phthalocyanines multicomponent ... See more keywords
Multicomponent synthesis, binding mode and structure-activity relationships of selective histone deacetylase 6 (HDAC6) inhibitors with bifurcated capping groups.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.9b01888
Abstract: The histone deacetylase 6 (HDAC6) is an emerging target for the treatment of cancer, neurodegenerative diseases, inflammation, and other diseases. Here, we present the multicomponent synthesis and structure-activity relationships of a series of tetrazole-based HDAC6… read more here.
Keywords: activity relationships; multicomponent synthesis; histone deacetylase; deacetylase hdac6 ... See more keywords
Palladium-Catalyzed Multicomponent Synthesis of Fully Substituted Alkylidene Furanones.
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DOI: 10.1021/acs.orglett.0c02578
Abstract: In the presence of a catalytic amount of Pd(OAc)2 and XantPhos, the three-component reaction of ynones, imines, and aryl iodides affords fully substituted alkylidene-furan-3(2H)-ones via a sequence of the Mannich reaction followed by chemo- and… read more here.
Keywords: fully substituted; multicomponent synthesis; synthesis fully; palladium catalyzed ... See more keywords
Diastereoselective, Multicomponent Synthesis of Pyrrolopyrazinoquinazolinones via a Tandem Quinazolinone Rearrangement/Intramolecular Ring Closure of Tautomeric (Z)-Benzamidines.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c01955
Abstract: An expedient route to enantiopure, diastereomeric pyrrolopyrazinoquinazolinones was developed following the discovery of a domino quinazolinone rearrangement-intramolecular cyclization of N-H benzamidines. A Ugi-Mumm-Staudinger sequence employing an optically pure proline derivative gave quinazolinones that, upon N-Boc… read more here.
Keywords: quinazolinone rearrangement; multicomponent synthesis; rearrangement intramolecular; diastereoselective multicomponent ... See more keywords
Multicomponent Synthesis of Tetrahydroisoquinolines.
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DOI: 10.1021/acs.orglett.8b01159
Abstract: A multicomponent synthesis of tetrahydroisoquinolines from carboxylic acids, alkynyl ethers, and dihydroisoquinolines is described. This process features readily available starting materials, simple experimental procedures for achievement of molecule complexity, and structural diversity. The preliminary control… read more here.
Keywords: multicomponent synthesis; synthesis tetrahydroisoquinolines;
Multicomponent Synthesis of Isoindolinones by RhIII Relay Catalysis: Synthesis of Pagoclone and Pazinaclone from Benzaldehyde.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.8b04026
Abstract: A practical one-pot isoindolinone synthesis enabled by RhIII catalysis was developed. The advantage of this protocol is that it does not require pre-preparation of amide substrates, because RhIII participates in two reactions independently. This mild,… read more here.
Keywords: multicomponent synthesis; catalysis; pagoclone pazinaclone; synthesis isoindolinones ... See more keywords
Ce@STANPs/ZrO2 as Nanocatalyst for Multicomponent Synthesis of Isatin-Derived Imidazoles under Green Reaction Conditions
Sign Up to like & getrecommendations! Published in 2018 at "ACS Omega"
DOI: 10.1021/acsomega.8b01043
Abstract: A highly efficient and recyclable catalyst, cerium-immobilized silicotungstic acid nanoparticle-impregnated zirconia (Ce@STANPs/ZrO2), has been synthesized. The catalytic activity of Ce@STANPs/ZrO2 was investigated for the first time in multicomponent synthesis of isatin-based imidazoles under microwave irradiation… read more here.
Keywords: synthesis isatin; microscopy; multicomponent synthesis; stanps zro2 ... See more keywords
Electrochemical multicomponent synthesis of 4-selanylpyrazoles under catalyst- and chemical-oxidant-free conditions
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DOI: 10.1039/d1gc00562f
Abstract: An electrochemical multicomponent reaction was established under catalyst-, chemical-oxidant-free and mild conditions, which provides an eco-friendly and simple protocol for constructing 4-selanylpyrazoles. A broad range of 4-selanylpyrazole derivatives could be obtained from easily available raw… read more here.
Keywords: catalyst chemical; electrochemical multicomponent; multicomponent synthesis; chemical oxidant ... See more keywords