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Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00499
Abstract: Herein, we report the first diaryliodonium salts promoted multicomponent 1,2,3-trifunctionalization of alkynes, where both the acetylenic bond and the adjacent nonactivated propargylic C(sp3)-H bond were functionalized synergistically to generate α-arylated enones with high chemo-, regio-,…
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Keywords:
multicomponent trifunctionalization;
chemo regio;
internal alkynes;