Multidimensional chemical control of CRISPR-Cas9.
Sign Up to like & getrecommendations! Published in 2017 at "Nature chemical biology"
DOI: 10.1038/nchembio.2224
Abstract: Cas9-based technologies have transformed genome engineering and the interrogation of genomic functions, but methods to control such technologies across numerous dimensions-including dose, time, specificity, and mutually exclusive modulation of multiple genes-are still lacking. We conferred… read more here.
Keywords: multidimensional chemical; crispr cas9; control; control crispr ... See more keywords
Primerize-2D: automated primer design for RNA multidimensional chemical mapping.
Sign Up to like & getrecommendations! Published in 2017 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btw814
Abstract: Summary Rapid RNA synthesis of comprehensive single mutant libraries and targeted multiple mutant libraries is enabling new multidimensional chemical approaches to solve RNA structures. PCR assembly of DNA templates and in vitro transcription allow synthesis… read more here.
Keywords: multidimensional chemical; primer design; automated primer; primerize automated ... See more keywords