Modeling Interventions to Reduce the Spread of Multidrug-Resistant Organisms Between Health Care Facilities in a Region
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.19212
Abstract: Key Points Question Which multidrug-resistant organism (MDRO) intervention is best to implement in a set of health care facilities to reduce the spread of MDROs regionwide? Findings In this computational simulation modeling study of 102… read more here.
Keywords: multidrug resistant; health care; care facilities; reduce spread ... See more keywords
Effectiveness of Fosfomycin for the Treatment of Multidrug-Resistant Escherichia coli Bacteremic Urinary Tract Infections
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.37277
Abstract: This randomized clinical trial investigates noninferiority of fosfomycin vs ceftriaxone or meropenem in achieving clinical and microbiological cure among patients with urinary tract infections due to multidrug-resistant Escherichia coli. read more here.
Keywords: escherichia coli; urinary tract; resistant escherichia; tract infections ... See more keywords
Treatment Outcomes Among Pregnant Patients With Multidrug-Resistant Tuberculosis
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DOI: 10.1001/jamanetworkopen.2022.16527
Abstract: Key Points Question What are the treatment outcomes and adverse events among pregnant patients with multidrug-resistant tuberculosis (MDR-TB)? Findings In a systematic review and meta-analysis of 10 studies including 275 pregnant patients with MDR-TB, the… read more here.
Keywords: pregnant patients; among pregnant; treatment outcomes; patients multidrug ... See more keywords
Multidrug-Resistant Pseudomonas aeruginosa Keratitis Associated With Artificial Tear Use.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2023.1109
Abstract: This case report describes severe multidrug-resistant Pseudomonas aeruginosa keratitis in a 72-year-old man after EzriCare artificial tear use. read more here.
Keywords: pseudomonas aeruginosa; tear use; artificial tear; aeruginosa keratitis ... See more keywords
Epigallocatechin‐3‐gallate sensitises multidrug‐resistant oral carcinoma xenografts to vincristine sulfate
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DOI: 10.1002/2211-5463.12905
Abstract: Oral squamous cell carcinoma (OSCC) is a very aggressive malignancy, and 50% of patients who receive curative treatment die from the disease or related complications within 5 years. Epigallocatechin‐3‐gallate (EGCG) is the most abundant bioactive… read more here.
Keywords: carcinoma; sensitises multidrug; epigallocatechin gallate; vincristine sulfate ... See more keywords
Multifunctional Molecular Beacon Micelles for Intracellular mRNA Imaging and Synergistic Therapy in Multidrug-Resistant Cancer Cells.
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DOI: 10.1002/adfm.201701027
Abstract: Multidrug resistance (MDR) resulting from overexpression of P-glycoprotein (Pgp) transporters increases the drug efflux and thereby limits the chemotherapeutic efficacy. It is desirable to administer both an MDR1 gene silencer and a chemotherapeutic agent in… read more here.
Keywords: multidrug; molecular beacon; dox; multidrug resistant ... See more keywords
Sonoactivated Chemodynamic Therapy: A Robust ROS Generation Nanotheranostic Eradicates Multidrug‐Resistant Bacterial Infection
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DOI: 10.1002/adfm.202003587
Abstract: Although ultrasound‐based therapeutic strategies have achieved great success in the battle against antibiotic‐resistant bacterial infections, various sonodynamic treatments still suffer from poor therapeutic efficiency, failing to completely eradicate infections. Thus, more potent strategies are urgently… read more here.
Keywords: resistant bacterial; bacterial infection; chemodynamic therapy; infection ... See more keywords
Visual Multifunctional Aggregation-Induced Emission-Based Bacterial Cellulose for Killing of Multidrug-Resistant Bacteria.
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DOI: 10.1002/adhm.202300045
Abstract: Multidrug resistant (MDR) bacteria-related wound infections have long been thorny issues. It is urgent to develop new antibacterial wound dressings that can not only prevent wounds from MDR bacteria infection but also promote wound healing.… read more here.
Keywords: induced emission; bacterial cellulose; multidrug resistant; aggregation induced ... See more keywords
Cationic Polysaccharide Conjugates as Antibiotic Adjuvants Resensitize Multidrug‐Resistant Bacteria and Prevent Resistance
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DOI: 10.1002/adma.202204065
Abstract: In recent years, traditional antibiotic efficacy has rapidly diminished due to the advent of multidrug‐resistant (MDR) bacteria, which poses severe threat to human life and globalized healthcare. Currently, the development cycle of new antibiotics cannot… read more here.
Keywords: polysaccharide conjugates; dex; dex pss30; cationic polysaccharide ... See more keywords
Biomimetic Bacteriophage‐Like Particles Formed from Probiotic Extracts and NO Donors for Eradicating Multidrug‐Resistant Staphylococcus aureus
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DOI: 10.1002/adma.202206134
Abstract: Effectively clearing multidrug‐resistant bacteria through nonantibiotic treatments is crucial for the recovery of infected tissues in favorable biological environments. Herein, a thermally responsive donor of cell‐messenger nitric oxide (NO) is combined with extracts of food‐grade… read more here.
Keywords: like particles; multidrug; staphylococcus aureus; multidrug resistant ... See more keywords
In Situ Sprayed Biotherapeutic Gel Containing Stable Microbial Communities for Efficient Anti‐Infection Treatment
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DOI: 10.1002/advs.202205480
Abstract: Systematic administration of antibiotics to treat infections often leads to the rapid evolution and spread of multidrug‐resistant bacteria. Here, an in situ‐formed biotherapeutic gel that controls multidrug‐resistant bacterial infections and accelerates wound healing is reported.… read more here.
Keywords: biotherapeutic gel; infection; gel; multidrug resistant ... See more keywords