Computation‐Guided Design of a Stimulus‐Responsive Multienzyme Supramolecular Assembly
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DOI: 10.1002/cbic.201700425
Abstract: The construction of stimulus-responsive supramolecular complexes of metabolic pathway enzymes, inspired by natural multienzyme assemblies (metabolons), provides an attractive avenue for efficient and spatiotemporally controllable one-pot biotransformations. We have constructed a phosphorylation- and optically responsive… read more here.
Keywords: stimulus; guided design; computation guided; multienzyme ... See more keywords
Synthetic Multienzyme Assemblies for Natural Product Biosynthesis
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DOI: 10.1002/cbic.202200518
Abstract: In nature, enzymes that catalyze sequential reactions are often assembled as clusters or complexes. The formation of multienzyme complexes, or metabolons, brings the enzyme active sites into proximity to promote intermediate transfer, decrease intermediate leakage,… read more here.
Keywords: multienzyme; synthetic multienzyme; multienzyme complexes; product ... See more keywords
Nutritive value of multienzyme supplemented cold-pressed camelina cake for pigs.
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DOI: 10.1093/jas/skx025
Abstract: Cold-pressed camelina cake (CPCC) is a fibrous co-product of camelina seed pressing and available for livestock feeding. However, information is lacking on the effect of supplementing fiber-degrading enzymes to CPCC-based diets on nutrient utilization by… read more here.
Keywords: camelina cake; multienzyme; cpcc; cold pressed ... See more keywords