Efficient biosynthesis of high-value succinic acid and 5-hydroxyleucine using a multienzyme cascade and whole-cell catalysis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b05529
Abstract: Succinic acid (SA), is applied in the food, chemical, and pharmaceutical industries. 5-Hydroxyleucine (5-HLeu) is a promising precursor for biosynthesis of antituberculosis drugs. Here, we designed a promising synthetic route for simultaneous production of SA… read more here.
Keywords: multienzyme cascade; succinic acid; whole cell; high value ... See more keywords
Covalently assembled ultrathin polymer nanocapsules to mimic a multienzyme-cascade antioxidative system
Sign Up to like & getrecommendations! Published in 2020 at "Materials Chemistry Frontiers"
DOI: 10.1039/d0qm00389a
Abstract: Ultrathin selenium-containing manganese-porphyrin-based polymer nanocapsules with both superoxide dismutase (SOD) and glutathione peroxidase (GPx) activity were successfully constructed through a covalent assembly strategy for mimicking the natural multienzyme-cascade antioxidative system. In this case, Mn-CATPyP (4,4′,4′′,4′′′-(Mn-porphyrin-5,10,15,20-tetrayl)tetrakis… read more here.
Keywords: multienzyme cascade; antioxidative system; polymer; cascade antioxidative ... See more keywords
Constructing a multienzyme cascade redox-neutral system for the synthesis of halogenated indoles.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00811d
Abstract: Inspired by biocatalytic retrosynthesis, a multienzyme cascade system containing alcohol dehydrogenase, flavin-dependent halogenase and flavin reductase was developed for the synthesis of several halogenated indoles starting from amino alcohol. This redox-neutral system not only omitted… read more here.
Keywords: system; neutral system; redox neutral; multienzyme cascade ... See more keywords