A Multifaceted Hit-Finding Approach Reveals Novel LC3 Family Ligands.
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DOI: 10.1021/acs.biochem.1c00682
Abstract: Autophagy-related proteins (Atgs) drive the lysosome-mediated degradation pathway, autophagy, to enable the clearance of dysfunctional cellular components and maintain homeostasis. In humans, this process is driven by the mammalian Atg8 (mAtg8) family of proteins comprising… read more here.
Keywords: reveals novel; multifaceted hit; family; approach reveals ... See more keywords