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Multifocal/multicentric breast cancer: Does each focus matter?

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1 Published in 2023 at "Cancer Medicine"

DOI: 10.1002/cam4.5626

Abstract: Multifocal (MF) and multicentric (MC) breast cancer cases have been increasingly diagnosed owing to the extensive use of improved preoperative breast imaging. The current tumor‐node‐metastasis staging system uses the dimension of the largest tumor and… read more here.

Keywords: cancer; breast; cancer focus; breast cancer ... See more keywords

Extreme Oncoplastic Surgery for Multifocal/Multicentric and Locally Advanced Breast Cancer

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0 Published in 2019 at "International Journal of Breast Cancer"

DOI: 10.1155/2019/4262589

Abstract: Introduction Breast conserving surgery (BCS) followed by radiation therapy (RT) has become the preferred alternative to mastectomy for patients with early stage breast cancer (BC). Randomized trials have confirmed equivalent locoregional control and overall survival… read more here.

Keywords: surgery; breast; cancer extreme; breast cancer ... See more keywords

Multifocal and multicentric breast cancer, is it time to think again?

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1 Published in 2020 at "Annals of the Royal College of Surgeons of England"

DOI: 10.1308/rcsann.2019.0109

Abstract: Multifocal multicentric breast cancer has traditionally been considered a contraindication to breast conserving surgery because of concerns regarding locoregional control and risk of disease recurrence. However, the evidence supporting this practice is limited. Increasingly, many… read more here.

Keywords: multicentric breast; multifocal multicentric; breast; breast cancer ... See more keywords

Does focal heterogeneity affect survival in postoperative ipsilateral multifocal and multicentric breast cancers?

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0 Published in 2022 at "Revista da Associacao Medica Brasileira"

DOI: 10.1590/1806-9282.20211168

Abstract: OBJECTIVE In multicentric/multifocal breast tumors, there may be immunological and histological differences between foci that may affect survival and treatment choice. We aimed to evaluate the effect of focal heterogeneity seen in multicentric/multifocal breast tumors… read more here.

Keywords: multicentric breast; affect survival; multifocal multicentric; breast cancers ... See more keywords

Association of Molecular Biomarker Heterogeneity With Treatment Pattern and Disease Outcomes in Multifocal or Multicentric Breast Cancer

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1 Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.833093

Abstract: Purpose This study aimed to evaluate the rates of estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), and Ki67 heterogeneity in multifocal or multicentric breast cancer (MMBC) and its association… read more here.

Keywords: heterogeneity; disease outcomes; group; treatment ... See more keywords