Versatile Electrochemiluminescence and Electrochemical "On-Off" Assays of Methyltransferases and Aflatoxin B1 Based on a Novel Multifunctional DNA Nanotube.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b05362
Abstract: Herein, a new multifunctional DNA nanotube (DNANT) was self-assembled and used to load Ru(phen)32+ and methylene blue (MB) as amplified signal probes for versatile electrochemiluminescence (ECL) and electrochemical (EC) "on-off" assays of Dam methylase (MTase)… read more here.
Keywords: signal probes; dna nanotube; dna; multifunctional dna ... See more keywords
Multifunctional DNA Tetrahedron for Alzheimer's Disease Mitochondria-Targeted Therapy by MicroRNA Regulation.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.3c03181
Abstract: The principal hallmark of Alzheimer's disease (AD) is neuron mitochondrial dysfunction, whereas mitochondrial miRNAs potentially play important roles. Nevertheless, efficacious mitochondria organelle therapeutic agents for treatment and management of AD are highly advisable. Herein, we… read more here.
Keywords: dna; alzheimer disease; mitochondria targeted; multifunctional dna ... See more keywords
Multifunctional DNA nanoprobe for tumor-targeted synergy therapy by integrating chemodynamic therapy with gene silencing
Sign Up to like & getrecommendations! Published in 2023 at "Nanoscale Horizons"
DOI: 10.1039/d2nh00575a
Abstract: Due to the high complexity, diversity and heterogeneity of tumor occurrence and development, multi-mode synergy therapy is more effective than single treatment mode to improve antitumor efficacy. And the multifunctional... read more here.
Keywords: nanoprobe tumor; synergy therapy; therapy; dna nanoprobe ... See more keywords