Multifunctional quercetin conjugated chitosan nano-micelles with P-gp inhibition and permeation enhancement of anticancer drug.
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DOI: 10.1016/j.carbpol.2018.09.020
Abstract: In this study, quercetin-chitosan conjugate (QT-CS) was synthesized for oral delivery of doxorubicin (DOX) to improve its oral bioavailability by increasing its water solubility, opening tight junction and bypassing the P-glycoprotein (P-gp). The prepared QT-CS… read more here.
Keywords: multifunctional quercetin; doxorubicin; conjugated chitosan; drug ... See more keywords