Multilevel virtual screening approach for discovery of thymidine phosphorylase inhibitors as potential anticancer agents
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DOI: 10.1016/j.molstruc.2021.131648
Abstract: Abstract Thymidine phosphorylase (TP) is an enzyme which catalyses the conversion of thymidine to thymine and 2-deoxy-α- d -ribose-1-phosphate. The 2-deoxy-α- d -ribose-1-phosphate is then dephosphorylated to the 2-deoxy-α- d -ribose, which can promote angiogenesis,… read more here.
Keywords: thymidine phosphorylase; virtual screening; thymidine; multilevel virtual ... See more keywords