Repurposing of an old drug: In vitro and in vivo efficacies of buparvaquone against Echinococcus multilocularis
Sign Up to like & getrecommendations! Published in 2018 at "International Journal for Parasitology: Drugs and Drug Resistance"
DOI: 10.1016/j.ijpddr.2018.10.011
Abstract: The metacestode stage of the fox tapeworm Echinococcus multilocularis causes the lethal disease alveolar echinococcosis. Current chemotherapeutic treatment options are based on benzimidazoles (albendazole and mebendazole), which are insufficient and hence alternative drugs are needed.… read more here.
Keywords: echinococcus multilocularis; vivo; drug; multilocularis ... See more keywords
Wind-borne dispersion of Echinococcus multilocularis eggs – a flight model
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DOI: 10.1017/s0022149x22000360
Abstract: Abstract The alveolar hydatid disease, also known as alveolar echinococcosis, of humans is certainly one of the most dangerous zoonoses worldwide. The disease is caused by Echinococcus multilocularis – the fox tapeworm. Red foxes (Vulpes… read more here.
Keywords: wind borne; multilocularis; multilocularis eggs; model ... See more keywords
Echinococcus multilocularis drives the polarization of macrophages by regulating the RhoA-MAPK signaling pathway and thus affects liver fibrosis
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DOI: 10.1080/21655979.2022.2056690
Abstract: ABSTRACT Echinococcus multilocularis is a small parasite that causes alveolar echinococcosis. It primarily induces liver disorder, such as liver fibrosis and even liver cancer, which severely endangers human lives. This study aims to explore the… read more here.
Keywords: liver fibrosis; soluble antigen; multilocularis; rhoa mapk ... See more keywords
Novel molecular diagnostic (PCR) diagnosis and outcome of intestinal Echinococcus multilocularis in a dog from western Canada.
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DOI: 10.2460/javma.23.03.0179
Abstract: OBJECTIVE To describe the novel PCR diagnosis and outcome of intestinal Echinococcus multilocularis in a dog. ANIMAL A 13-month-old female intact dog with naturally occurring intestinal E multilocularis. CLINICAL PRESENTATION, PROGRESSION, AND PROCEDURES The 13-month-old… read more here.
Keywords: diagnosis outcome; pcr diagnosis; multilocularis; outcome intestinal ... See more keywords