Multimodal epigenetic changes and altered NEUROD1 chromatin binding in the mouse hippocampus underlie FOXG1 syndrome
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DOI: 10.1073/pnas.2122467120
Abstract: Significance Mutations in the FOXG1 gene cause a rare neurodevelopmental disorder called “FOXG1-syndrome”. FOXG1 is a key instructor of the developing telencephalon, and patients present with various phenotypes including microcephaly, seizures, and cognitive dysfunctions. We… read more here.
Keywords: multimodal epigenetic; foxg1 syndrome; mouse; syndrome ... See more keywords