Comparative analysis of dermal collagen and lipids in cereblon ablated mice using a multimodal nonlinear optical system
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202200139
Abstract: By utilizing a multimodal nonlinear optical system that combines coherent anti‐Stokes Raman scattering and second harmonic generation to investigate biological characteristics of dermal tissues ex vivo, we demonstrate the potential feasibility of using this optical… read more here.
Keywords: system; cereblon; nonlinear optical; collagen ... See more keywords
The role of altered lipid composition and distribution in liver fibrosis revealed by multimodal nonlinear optical microscopy
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.abq2937
Abstract: Intracellular lipid accumulation is commonly seen in fibrotic livers, but its exact role in liver fibrosis remains elusive. Here, we established a multimodal nonlinear optical microscopy to quantitatively map distribution of biomolecules in fibrotic livers.… read more here.
Keywords: liver fibrosis; role; nonlinear optical; microscopy ... See more keywords
Label-free multimodal nonlinear optical microscopy reveals features of bone composition in pathophysiological conditions
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.1042680
Abstract: Bone tissue features a complex microarchitecture and biomolecular composition, which determine biomechanical properties. In addition to state-of-the-art technologies, innovative optical approaches allowing the characterization of the bone in native, label-free conditions can provide new, multi-level… read more here.
Keywords: label free; nonlinear optical; bone; microscopy ... See more keywords
Multimodal nonlinear optical imaging ofCaenorhabditis eleganswith multiplex coherent anti-Stokes Raman scattering, third-harmonic generation, second-harmonic generation, and two-photon excitation fluorescence
Sign Up to like & getrecommendations! Published in 2020 at "Applied Physics Express"
DOI: 10.35848/1882-0786/ab9711
Abstract: Multimodal nonlinear optical microscopy was applied to the nematode Caenorhabditis elegans (C. elegans). Transgenic worms expressing the yellow fluorescent protein (YFP) variant Venus underwent analyses. The lipid and protein distribution was clearly visualized using multiplex… read more here.
Keywords: microscopy; harmonic generation; multimodal nonlinear; generation ... See more keywords