Articles with "multimodal parameter" as a keyword



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Development of visual predictive checks accounting for multimodal parameter distributions in mixture models

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Published in 2019 at "Journal of Pharmacokinetics and Pharmacodynamics"

DOI: 10.1007/s10928-019-09632-9

Abstract: The assumption of interindividual variability being unimodally distributed in nonlinear mixed effects models does not hold when the population under study displays multimodal parameter distributions. Mixture models allow the identification of parameters characteristic to a… read more here.

Keywords: multimodal parameter; visual predictive; mixture models; parameter distributions ... See more keywords