Frailty, multimorbidity and polypharmacy
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DOI: 10.1016/j.mpmed.2020.12.010
Abstract: Abstract Frailty and multimorbidity are interrelated complex syndromes. Individuals living with frailty are likely to be multimorbid, but not all multimorbid individuals are frail. Frailty and multimorbidity are principal causes of polypharmacy. In combination, they… read more here.
Keywords: multimorbid; multimorbidity polypharmacy; frailty; frailty multimorbidity ... See more keywords
Cost-effectiveness of a structured medication review approach for multimorbid older adults: Within-trial analysis of the OPERAM study
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DOI: 10.1371/journal.pone.0265507
Abstract: Background Inappropriate polypharmacy has been linked with adverse outcomes in older, multimorbid adults. OPERAM is a European cluster-randomized trial aimed at testing the effect of a structured pharmacotherapy optimization intervention on preventable drug-related hospital admissions… read more here.
Keywords: cost; trial; within trial; intervention ... See more keywords
Development and validation of a new prognostic index for mortality risk in multimorbid adults
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DOI: 10.1371/journal.pone.0271923
Abstract: Context Multimorbidity is highly prevalent among older adults and associated with a high mortality. Prediction of mortality in multimorbid people would be clinically useful but there is no mortality risk index designed for this population.… read more here.
Keywords: index; year; mortality; risk ... See more keywords